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Open Access
Peer-reviewed
Research Article
ISG15 deficiency restricts HIV-1 infection
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Denise Jurczyszak,
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America
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Lara Manganaro,
Roles Data curation, Formal analysis, Investigation, Writing – review & editing
Affiliations INGM-Istituto Nazionale di Genetica Molecolare, Virology, Milan, Italy, Department of Pharmacological and Biomolecular Sciences (DiSFeB), University of MIlan, Milan, Italy
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Sofija Buta,
Roles Data curation, Investigation
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America
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Conor Gruber,
Roles Investigation, Writing – review & editing
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America
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Marta Martin-Fernandez,
Roles Data curation, Investigation, Writing – review & editing
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America
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Justin Taft,
Roles Formal analysis
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America
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Roosheel S. Patel,
Roles Data curation, Formal analysis, Writing – original draft, Writing – review & editing
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America
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Melissa Cipolla,
Roles Data curation, Formal analysis
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America
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Hala Alshammary,
Roles Investigation
Affiliation Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America
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Lubbertus C. F. Mulder,
Roles Funding acquisition, Resources, Supervision, Writing – review & editing
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America
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Ravi Sachidanandam,
Roles Investigation, Resources
Affiliation Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America
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Dusan Bogunovic ,
Contributed equally to this work with: Dusan Bogunovic, Viviana Simon
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: dusan.bogunovic@mssm.edu (DB); viviana.simon@mssm.edu (VS)
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Center for Inborn Errors of Immunity, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America, Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America
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Viviana Simon
Contributed equally to this work with: Dusan Bogunovic, Viviana Simon
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: dusan.bogunovic@mssm.edu (DB); viviana.simon@mssm.edu (VS)
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America, Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York City, New York, United States of America
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ISG15 deficiency restricts HIV-1 infection
- Denise Jurczyszak,
- Lara Manganaro,
- Sofija Buta,
- Conor Gruber,
- Marta Martin-Fernandez,
- Justin Taft,
- Roosheel S. Patel,
- Melissa Cipolla,
- Hala Alshammary,
- Lubbertus C. F. Mulder
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- Published: March 25, 2022
- https://doi.org/10.1371/journal.ppat.1010405