Single-cell transcriptomics reveals expression profiles of Trypanosoma brucei sexual stages

Virginia M. Howick; Lori Peacock; Chris Kay; Clare Collett; Wendy Gibson; Mara K. N. Lawniczak

doi:10.1371/journal.ppat.1010346

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Peer-reviewed

Research Article

Single-cell transcriptomics reveals expression profiles of Trypanosoma brucei sexual stages

Virginia M. Howick ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

* E-mail: Virginia.Howick@glasgow.ac.uk

Affiliations Institute of Biodiversity, Animal Health, and Comparative Medicine, University of Glasgow, Glasgow, United Kingdom, Wellcome Centre for Integrative Parasitology, University of Glasgow, Glasgow, United Kingdom, Parasites and Microbes Programme, Wellcome Sanger Institute, Hinxton, United Kingdom
⨯
Lori Peacock,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations School of Biological Sciences, University of Bristol, Bristol, United Kingdom, Bristol Veterinary School, University of Bristol, Langford, United Kingdom
⨯
Chris Kay,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation School of Biological Sciences, University of Bristol, Bristol, United Kingdom
⨯
Clare Collett,

Roles Investigation, Methodology, Writing – review & editing

Current address: UK Health Security Agency, Porton Down, United Kingdom

Affiliation School of Biological Sciences, University of Bristol, Bristol, United Kingdom
⨯
Wendy Gibson ,

Contributed equally to this work with: Wendy Gibson, Mara K. N. Lawniczak

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation School of Biological Sciences, University of Bristol, Bristol, United Kingdom
⨯
Mara K. N. Lawniczak

Contributed equally to this work with: Wendy Gibson, Mara K. N. Lawniczak

Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

Affiliation Parasites and Microbes Programme, Wellcome Sanger Institute, Hinxton, United Kingdom
⨯

Single-cell transcriptomics reveals expression profiles of Trypanosoma brucei sexual stages

Virginia M. Howick,
Lori Peacock,
Chris Kay,
Clare Collett,
Wendy Gibson,
Mara K. N. Lawniczak

Published: March 7, 2022
https://doi.org/10.1371/journal.ppat.1010346
See the preprint

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Trypanosoma
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Salivary glands
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Transcriptome analysis
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Gene expression
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Marker genes
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Trypanosoma brucei gambiense
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