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Open Access
Peer-reviewed
Research Article
SARS-CoV-2-specific T cells generated for adoptive immunotherapy are capable of recognizing multiple SARS-CoV-2 variants
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Archana Panikkar,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Katie E. Lineburg,
Roles Conceptualization, Funding acquisition, Investigation, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Jyothy Raju,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Keng Yih Chew,
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia Queensland, Australia
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George R. Ambalathingal,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Sweera Rehan,
Roles Investigation, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Srividhya Swaminathan,
Roles Investigation, Writing – review & editing
Affiliations QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia, Faculty of Medicine, The University of Queensland, Herston, Queensland, Australia
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Pauline Crooks,
Roles Investigation, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Laetitia Le Texier,
Roles Investigation, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Leone Beagley,
Roles Investigation, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Shannon Best,
Roles Investigation, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Matthew Solomon,
Roles Investigation, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Katherine K. Matthews,
Roles Conceptualization, Project administration, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Sriganesh Srihari,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Michelle A. Neller,
Roles Conceptualization, Project administration, Supervision, Writing – review & editing
Affiliation QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
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Kirsty R. Short,
Roles Conceptualization, Data curation, Supervision, Writing – review & editing
Affiliations School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia Queensland, Australia, Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia Queensland, Australia
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Rajiv Khanna,
Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing
Affiliations QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia, Faculty of Medicine, The University of Queensland, Herston, Queensland, Australia
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Corey Smith
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft
* E-mail: corey.smith@qimrberghofer.edu.au
Affiliations QIMR Berghofer Centre for Immunotherapy and Vaccine Development and Translational and Human Immunology Laboratory, Department of Immunology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia, Faculty of Medicine, The University of Queensland, Herston, Queensland, Australia
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SARS-CoV-2-specific T cells generated for adoptive immunotherapy are capable of recognizing multiple SARS-CoV-2 variants
- Archana Panikkar,
- Katie E. Lineburg,
- Jyothy Raju,
- Keng Yih Chew,
- George R. Ambalathingal,
- Sweera Rehan,
- Srividhya Swaminathan,
- Pauline Crooks,
- Laetitia Le Texier,
- Leone Beagley
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- Published: February 14, 2022
- https://doi.org/10.1371/journal.ppat.1010339