Host MOV10 is induced to restrict herpes simplex virus 1 lytic infection by promoting type I interferon response

Xiyuan Yang; Ze Xiang; Zeyu Sun; Feiyang Ji; Keyi Ren; Dongli Pan

doi:10.1371/journal.ppat.1010301

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Open Access

Peer-reviewed

Research Article

Host MOV10 is induced to restrict herpes simplex virus 1 lytic infection by promoting type I interferon response

Xiyuan Yang,

Roles Data curation, Formal analysis, Investigation, Writing – original draft

Affiliations State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China, Department of Medical Microbiology and Parasitology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

https://orcid.org/0000-0002-1662-266X

⨯
Ze Xiang,

Roles Data curation, Formal analysis

Affiliations State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China, Department of Medical Microbiology and Parasitology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

https://orcid.org/0000-0002-0897-4550

⨯
Zeyu Sun,

Roles Formal analysis, Methodology

Affiliation State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
⨯
Feiyang Ji,

Roles Methodology

Affiliation State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
⨯
Keyi Ren,

Roles Methodology

Affiliation State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
⨯
Dongli Pan

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – review & editing

* E-mail: pandongli@zju.edu.cn

Affiliations State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China, Department of Medical Microbiology and Parasitology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

https://orcid.org/0000-0002-0421-6242

⨯

Host MOV10 is induced to restrict herpes simplex virus 1 lytic infection by promoting type I interferon response

Xiyuan Yang,
Ze Xiang,
Zeyu Sun,
Feiyang Ji,
Keyi Ren,
Dongli Pan

Published: February 14, 2022
https://doi.org/10.1371/journal.ppat.1010301

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Transfection
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Herpes simplex virus-1
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Plasmid construction
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