MicroRNA-200c-targeted contactin 1 facilitates the replication of influenza A virus by accelerating the degradation of MAVS

Shuai Xu; Lu Han; Yanli Wei; Bo Zhang; Qian Wang; Junwen Liu; Minxuan Liu; Zhaoshan Chen; Zhengxiang Wang; Hualan Chen; Qiyun Zhu

doi:10.1371/journal.ppat.1010299

Loading metrics

Open Access

Peer-reviewed

Research Article

MicroRNA-200c-targeted contactin 1 facilitates the replication of influenza A virus by accelerating the degradation of MAVS

Shuai Xu,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation State Key Laboratory of Veterinary Etiological Biology, College of Animal Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, PR China
⨯
Lu Han,

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

Affiliation State Key Laboratory of Veterinary Etiological Biology, College of Animal Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, PR China
⨯
Yanli Wei,

Roles Investigation, Methodology

Affiliation State Key Laboratory of Veterinary Etiological Biology, College of Animal Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, PR China
⨯
Bo Zhang,

Roles Investigation, Methodology

Affiliations State Key Laboratory of Veterinary Etiological Biology, College of Animal Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, PR China, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, PR China
⨯
Qian Wang,

Roles Investigation

Affiliation State Key Laboratory of Veterinary Etiological Biology, College of Animal Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, PR China
⨯
Junwen Liu,

Roles Investigation

Affiliation State Key Laboratory of Veterinary Etiological Biology, College of Animal Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, PR China
⨯
Minxuan Liu,

Roles Investigation

Affiliation State Key Laboratory of Veterinary Etiological Biology, College of Animal Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, PR China
⨯
Zhaoshan Chen,

Roles Investigation

Affiliation State Key Laboratory of Veterinary Etiological Biology, College of Animal Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, PR China
⨯
Zhengxiang Wang,

Roles Investigation

Affiliation State Key Laboratory of Veterinary Etiological Biology, College of Animal Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, PR China
⨯
Hualan Chen,

Roles Resources

Affiliation State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, PR China
⨯
Qiyun Zhu

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: zhuqiyun@caas.cn

Affiliation State Key Laboratory of Veterinary Etiological Biology, College of Animal Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, PR China

https://orcid.org/0000-0003-3748-948X

⨯

MicroRNA-200c-targeted contactin 1 facilitates the replication of influenza A virus by accelerating the degradation of MAVS

Shuai Xu,
Lu Han,
Yanli Wei,
Bo Zhang,
Qian Wang,
Junwen Liu,
Minxuan Liu,
Zhaoshan Chen,
Zhengxiang Wang,
Hualan Chen

Published: February 16, 2022
https://doi.org/10.1371/journal.ppat.1010299

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Influenza A virus
Is the Subject Area "Influenza A virus" applicable to this article?

Thanks for your feedback.
Immunoblotting
Is the Subject Area "Immunoblotting" applicable to this article?

Thanks for your feedback.
Viral replication
Is the Subject Area "Viral replication" applicable to this article?

Thanks for your feedback.
Ubiquitination
Is the Subject Area "Ubiquitination" applicable to this article?

Thanks for your feedback.
Interferons
Is the Subject Area "Interferons" applicable to this article?

Thanks for your feedback.
Co-immunoprecipitation
Is the Subject Area "Co-immunoprecipitation" applicable to this article?

Thanks for your feedback.
Plasmid construction
Is the Subject Area "Plasmid construction" applicable to this article?

Thanks for your feedback.