SARS-CoV-2 variants with reduced infectivity and varied sensitivity to the BNT162b2 vaccine are developed during the course of infection

Dina Khateeb; Tslil Gabrieli; Bar Sofer; Adi Hattar; Sapir Cordela; Abigael Chaouat; Ilia Spivak; Izabella Lejbkowicz; Ronit Almog; Michal Mandelboim; Yotam Bar-On

doi:10.1371/journal.ppat.1010242

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Open Access

Peer-reviewed

Research Article

SARS-CoV-2 variants with reduced infectivity and varied sensitivity to the BNT162b2 vaccine are developed during the course of infection

Dina Khateeb,

Roles Investigation

Affiliation Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
⨯
Tslil Gabrieli,

Roles Investigation

Affiliation Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel

https://orcid.org/0000-0003-0368-3209

⨯
Bar Sofer,

Roles Investigation

Affiliation Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
⨯
Adi Hattar,

Roles Investigation

Affiliation Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
⨯
Sapir Cordela,

Roles Investigation

Affiliation Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
⨯
Abigael Chaouat,

Roles Resources

Affiliation The Concern Foundation Laboratories at the Lautenberg Center for Immunology and Cancer Research, Institute for Medical Research Israel Canada (IMRIC), The Hebrew University Hadassah Medical School, Jerusalem, Israel
⨯
Ilia Spivak,

Roles Investigation

Affiliation Department of Pediatrics B, Ruth Rappaport Children’s Hospital, Rambam Health Care Campus, Haifa, Israel
⨯
Izabella Lejbkowicz,

Roles Resources

Affiliation Epidemiology Unit and Biobank, Rambam Health Care Campus, Haifa, Israel
⨯
Ronit Almog,

Roles Resources

Affiliation Epidemiology Unit and Biobank, Rambam Health Care Campus, Haifa, Israel

https://orcid.org/0000-0002-9190-515X

⨯
Michal Mandelboim,

Roles Resources

Affiliation Central Virology Laboratory, Sheba Medical Center, Tel Hashomer, Israel
⨯
Yotam Bar-On

Roles Supervision

* E-mail: ybaron@technion.ac.il

Affiliation Department of Immunology, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel

https://orcid.org/0000-0003-4378-707X

⨯

SARS-CoV-2 variants with reduced infectivity and varied sensitivity to the BNT162b2 vaccine are developed during the course of infection

Dina Khateeb,
Tslil Gabrieli,
Bar Sofer,
Adi Hattar,
Sapir Cordela,
Abigael Chaouat,
Ilia Spivak,
Izabella Lejbkowicz,
Ronit Almog,
Michal Mandelboim

Published: January 12, 2022
https://doi.org/10.1371/journal.ppat.1010242

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