Viral RNA N⁶-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus

• Miaoge Xue,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Yuexiu Zhang,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Haitao Wang,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliations Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America, Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Boston, Massachusetts, United States of America

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• Elizabeth L. Kairis,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Mijia Lu,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

  https://orcid.org/0000-0002-4438-980X

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• Sadeem Ahmad,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliations Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America, Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Boston, Massachusetts, United States of America

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• Zayed Attia,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

  https://orcid.org/0000-0001-6930-8343

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• Olivia Harder,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

  https://orcid.org/0000-0002-5420-0134

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• Zijie Zhang,

  Roles Data curation, Formal analysis, Methodology, Software, Writing – review & editing

  Affiliation Department of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois, United States of America

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• Jiangbo Wei,

  Roles Methodology, Software, Writing – review & editing

  Affiliation Department of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois, United States of America

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• Phylip Chen,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, Ohio, United States of America

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• Youling Gao,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliation Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Mark E. Peeples,

  Roles Data curation, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliations Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, Ohio, United States of America, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America

  https://orcid.org/0000-0002-4582-317X

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• Amit Sharma,

  Roles Data curation, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Prosper Boyaka,

  Roles Data curation, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Chuan He,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Software, Supervision, Writing – review & editing

  Affiliations Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, The University of Chicago, Chicago, Illinois, United States of America

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• Sun Hur,

  Roles Data curation, Funding acquisition, Methodology, Supervision, Validation, Writing – review & editing

  Affiliations Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Boston Children’s Hospital, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0001-5005-5550

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• Stefan Niewiesk,

  Roles Data curation, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  Affiliation Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

  https://orcid.org/0000-0003-4487-073X

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•  [ ... ],
• Jianrong Li

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: li.926@osu.edu

  Affiliation Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America

  https://orcid.org/0000-0002-7130-1084

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