Cerebrospinal fluid CD4+ T cell infection in humans and macaques during acute HIV-1 and SHIV infection

• Vishakha Sharma,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft

  Current address: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

  Affiliations Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America

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• Matthew Creegan,

  Roles Methodology

  Affiliations Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0002-4205-466X

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• Andrey Tokarev,

  Roles Methodology

  Current address: US Army Medical Department, Dwight D. Eisenhower Army Medical Center, Ft Gordon, Georgia, United States of America

  Affiliations Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0002-2616-691X

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• Denise Hsu,

  Roles Conceptualization, Writing – review & editing

  Affiliations Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America, Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

  https://orcid.org/0000-0001-7530-0508

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• Bonnie M. Slike,

  Roles Investigation

  Affiliations Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0003-4132-4637

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• Carlo Sacdalan,

  Roles Investigation

  Affiliation Institute of HIV Research and Innovation, Bangkok, Thailand

  https://orcid.org/0000-0002-5839-4837

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• Phillip Chan,

  Roles Investigation

  Affiliation Institute of HIV Research and Innovation, Bangkok, Thailand

  https://orcid.org/0000-0002-4071-4409

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• Serena Spudich,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Department of Neurology, Yale University, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0001-6032-3950

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• Jintanat Ananworanich,

  Roles Funding acquisition

  Current address: Moderna, Inc., Cambridge, Massachusetts, United States of America

  Affiliations Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America

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• Michael A. Eller,

  Roles Supervision, Writing – review & editing

  Current address: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

  Affiliations Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America

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• Shelly J. Krebs,

  Roles Supervision, Writing – review & editing

  Affiliations Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0003-1136-1760

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• Sandhya Vasan,

  Roles Conceptualization, Writing – review & editing

  Affiliations Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America, Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

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• Diane L. Bolton ,

  Roles Conceptualization, Formal analysis, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: DBolton@hivresearch.org

  Affiliations Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0003-1897-499X

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• the RV254/SEARCH010 and RV304/SEARCH013 Study Teams