Single-cell transcriptome profiling and the use of AID deficient mice reveal that B cell activation combined with antibody class switch recombination and somatic hypermutation do not benefit the control of experimental trypanosomosis

• Hang Thi Thu Nguyen,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium, Laboratory for Biomedical Research, Ghent University Global Campus, Incheon, South Korea, Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium

  https://orcid.org/0000-0002-1642-4700

  ⨯
• Robin B. Guevarra,

  Roles Software, Writing – original draft

  Affiliation Laboratory for Biomedical Research, Ghent University Global Campus, Incheon, South Korea

  https://orcid.org/0000-0002-4809-1816

  ⨯
• Stefan Magez ,

  Contributed equally to this work with: Stefan Magez, Magdalena Radwanska

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: Stefan.Magez@ghent.ac.kr (SM); magdalena.radwanska@ghent.ac.kr (MR)

  Affiliations Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium, Laboratory for Biomedical Research, Ghent University Global Campus, Incheon, South Korea, Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium

  https://orcid.org/0000-0003-3760-7968

  ⨯
• Magdalena Radwanska

  Contributed equally to this work with: Stefan Magez, Magdalena Radwanska

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: Stefan.Magez@ghent.ac.kr (SM); magdalena.radwanska@ghent.ac.kr (MR)

  Affiliations Laboratory for Biomedical Research, Ghent University Global Campus, Incheon, South Korea, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium

  ⨯