Novel regulators of PrP^C biosynthesis revealed by genome-wide RNA interference

• Daniel Heinzer ,

  Contributed equally to this work with: Daniel Heinzer, Merve Avar

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0002-3282-4042

  ⨯
• Merve Avar ,

  Contributed equally to this work with: Daniel Heinzer, Merve Avar

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0003-4665-5558

  ⨯
• Daniel Patrick Pease ,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  ¶‡ DPP and AD are both second authors

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0001-6632-7063

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• Ashutosh Dhingra ,

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Writing – review & editing

  ¶‡ DPP and AD are both second authors

  Affiliation German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany

  ⨯
• Jiang-An Yin,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0002-2134-8693

  ⨯
• Elke Schaper,

  Roles Formal analysis, Resources, Software, Writing – review & editing

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0003-3734-2496

  ⨯
• Berre Doğançay,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  ⨯
• Marc Emmenegger,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0002-6073-8811

  ⨯
• Anna Spinelli,

  Roles Resources, Writing – review & editing

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0002-8829-7405

  ⨯
• Kevin Maggi,

  Roles Resources, Writing – review & editing

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  ⨯
• Andra Chincisan,

  Roles Formal analysis, Software, Writing – review & editing

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0003-3170-6500

  ⨯
• Simon Mead,

  Roles Data curation, Formal analysis

  Affiliation MRC Prion Unit at UCL, Institute of Prion Diseases, London, United Kingdom

  https://orcid.org/0000-0002-4326-1468

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• Simone Hornemann,

  Roles Supervision, Writing – review & editing

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0002-2674-9891

  ⨯
• Peter Heutink,

  Roles Supervision, Writing – review & editing

  Affiliation German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany

  https://orcid.org/0000-0001-5218-1737

  ⨯
• Adriano Aguzzi

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: adriano.aguzzi@usz.ch

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  https://orcid.org/0000-0002-0344-6708

  ⨯