Comparison of transcriptional profiles of Treponema pallidum during experimental infection of rabbits and in vitro culture: Highly similar, yet different

Bridget D. De Lay; Todd A. Cameron; Nicholas R. De Lay; Steven J. Norris; Diane G. Edmondson

doi:10.1371/journal.ppat.1009949

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Peer-reviewed

Research Article

Comparison of transcriptional profiles of Treponema pallidum during experimental infection of rabbits and in vitro culture: Highly similar, yet different

Bridget D. De Lay ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

* E-mail: Bridget.D.DeLay@uth.tmc.edu

Affiliation Department of Pathology and Laboratory Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

https://orcid.org/0000-0003-1354-1407

⨯
Todd A. Cameron,

Roles Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliation Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

https://orcid.org/0000-0002-6608-6551

⨯
Nicholas R. De Lay,

Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

Affiliation Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

https://orcid.org/0000-0003-2249-7073

⨯
Steven J. Norris,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

Affiliations Department of Pathology and Laboratory Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America, Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America
⨯
Diane G. Edmondson

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Resources, Supervision, Writing – review & editing

Affiliation Department of Pathology and Laboratory Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

https://orcid.org/0000-0003-3702-9715

⨯

Comparison of transcriptional profiles of Treponema pallidum during experimental infection of rabbits and in vitro culture: Highly similar, yet different

Bridget D. De Lay,
Todd A. Cameron,
Nicholas R. De Lay,
Steven J. Norris,
Diane G. Edmondson

Published: September 27, 2021
https://doi.org/10.1371/journal.ppat.1009949

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Rabbits
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Treponema pallidum
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DNA-binding proteins
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Gene expression
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Protein translation
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Protein synthesis
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Transmembrane transport proteins
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RNA sequencing
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