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Open Access
Peer-reviewed
Research Article
Protective CD4+ Th1 cell-mediated immunity is reliant upon execution of effector function prior to the establishment of the pathogen niche
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Leah S. Hohman,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations Snyder Institute for Chronic Diseases; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, Calgary, Alberta, Canada, Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine; University of Calgary, Calgary, Alberta, Canada
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Zhirong Mou,
Roles Resources
Affiliation Department of Immunology, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
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Matheus B. Carneiro,
Roles Investigation, Methodology
Affiliations Snyder Institute for Chronic Diseases; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, Calgary, Alberta, Canada, Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine; University of Calgary, Calgary, Alberta, Canada
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Gabriel Ferland,
Roles Investigation
Affiliations Snyder Institute for Chronic Diseases; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, Calgary, Alberta, Canada, Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine; University of Calgary, Calgary, Alberta, Canada
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Rachel M. Kratofil,
Roles Investigation
Affiliations Snyder Institute for Chronic Diseases; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, Calgary, Alberta, Canada, Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada
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Paul Kubes,
Roles Resources, Writing – review & editing
Affiliations Snyder Institute for Chronic Diseases; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, Calgary, Alberta, Canada, Department of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada
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Jude E. Uzonna,
Roles Resources
Affiliation Department of Immunology, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
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Nathan C. Peters
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: ncpeters@ucalgary.ca
Affiliations Snyder Institute for Chronic Diseases; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, Calgary, Alberta, Canada, Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine; University of Calgary, Calgary, Alberta, Canada
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Protective CD4+ Th1 cell-mediated immunity is reliant upon execution of effector function prior to the establishment of the pathogen niche
- Leah S. Hohman,
- Zhirong Mou,
- Matheus B. Carneiro,
- Gabriel Ferland,
- Rachel M. Kratofil,
- Paul Kubes,
- Jude E. Uzonna,
- Nathan C. Peters
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- Published: September 20, 2021
- https://doi.org/10.1371/journal.ppat.1009944