The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape

• Charlotte Vandermeulen,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliations Laboratory of Viral Interactomes, GIGA Institute, University of Liege, Liege, Belgium, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Laboratory of Gene Expression and Cancer, GIGA Institute, University of Liege, Liege, Belgium

  https://orcid.org/0000-0001-5026-9567

  ⨯
• Tina O’Grady ,

  Contributed equally to this work with: Tina O’Grady, Jerome Wayet, Bartimee Galvan

  Roles Formal analysis, Methodology, Software, Writing – review & editing

  Affiliation Laboratory of Gene Expression and Cancer, GIGA Institute, University of Liege, Liege, Belgium

  https://orcid.org/0000-0002-1283-0293

  ⨯
• Jerome Wayet ,

  Contributed equally to this work with: Tina O’Grady, Jerome Wayet, Bartimee Galvan

  Roles Formal analysis, Investigation, Methodology

  Affiliation Unit of Animal Genomics, GIGA, Université de Liège (ULiège), Liège, Belgium

  https://orcid.org/0000-0001-5113-1877

  ⨯
• Bartimee Galvan ,

  Contributed equally to this work with: Tina O’Grady, Jerome Wayet, Bartimee Galvan

  Roles Investigation, Methodology

  Affiliation Laboratory of Gene Expression and Cancer, GIGA Institute, University of Liege, Liege, Belgium

  ⨯
• Sibusiso Maseko,

  Roles Investigation, Methodology

  Affiliation Laboratory of Viral Interactomes, GIGA Institute, University of Liege, Liege, Belgium

  https://orcid.org/0000-0001-7025-6106

  ⨯
• Majid Cherkaoui,

  Roles Methodology

  Affiliation Laboratory of Viral Interactomes, GIGA Institute, University of Liege, Liege, Belgium

  ⨯
• Alice Desbuleux,

  Roles Methodology

  Affiliations Laboratory of Viral Interactomes, GIGA Institute, University of Liege, Liege, Belgium, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

  ⨯
• Georges Coppin,

  Roles Data curation, Formal analysis

  Affiliations Laboratory of Viral Interactomes, GIGA Institute, University of Liege, Liege, Belgium, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

  ⨯
• Julien Olivet,

  Roles Visualization, Writing – review & editing

  Affiliations Laboratory of Viral Interactomes, GIGA Institute, University of Liege, Liege, Belgium, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0003-4115-5546

  ⨯
• Lamya Ben Ameur,

  Roles Formal analysis, Methodology

  Affiliation Laboratory of Biology and Modeling of the Cell, CNRS UMR 5239, INSERM U1210, University of Lyon, Lyon, France

  https://orcid.org/0000-0002-2975-8822

  ⨯
• Keisuke Kataoka,

  Roles Data curation, Resources

  Affiliation Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

  https://orcid.org/0000-0002-8263-9902

  ⨯
• Seishi Ogawa,

  Roles Data curation, Resources

  Affiliation Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

  ⨯
• Olivier Hermine,

  Roles Resources

  Affiliation Service Hématologie Adultes, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants Malades, Université de Paris, Laboratoire d’onco-hématologie, Institut Necker-Enfants Malades, INSERM U1151, Université de Paris, Paris, France

  ⨯
• Ambroise Marcais,

  Roles Resources

  Affiliation Service Hématologie Adultes, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants Malades, Université de Paris, Laboratoire d’onco-hématologie, Institut Necker-Enfants Malades, INSERM U1151, Université de Paris, Paris, France

  https://orcid.org/0000-0002-6844-7920

  ⨯
• Marc Thiry,

  Roles Formal analysis, Investigation, Methodology, Visualization

  Affiliation Unit of Cell and Tissue Biology, GIGA Institute, University of Liege, Liege, Belgium

  https://orcid.org/0000-0002-4944-584X

  ⨯
• Franck Mortreux,

  Roles Formal analysis, Methodology, Resources, Supervision

  Affiliation Laboratory of Biology and Modeling of the Cell, CNRS UMR 5239, INSERM U1210, University of Lyon, Lyon, France

  https://orcid.org/0000-0002-4840-021X

  ⨯
• Michael A. Calderwood,

  Roles Supervision

  Affiliations Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0001-6475-1418

  ⨯
• Johan Van Weyenbergh,

  Roles Data curation, Formal analysis, Funding acquisition, Methodology, Resources

  Affiliation Laboratory of Clinical and Epidemiological Virology, Rega Institute for Medical Research, Department of Microbiology, Immunology and Transplantation, Catholic University of Leuven, Leuven, Belgium

  https://orcid.org/0000-0003-3234-8426

  ⨯
• Jean-Marie Peloponese,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Université Montpellier, IRIM CNRS UMR 9004 Montpellier, France

  https://orcid.org/0000-0002-9677-9703

  ⨯
• Benoit Charloteaux,

  Roles Formal analysis, Investigation, Methodology, Software, Supervision, Writing – review & editing

  Affiliations Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Human Genetics, CHU of Liege, University of Liege, Liege, Belgium

  https://orcid.org/0000-0003-4282-9688

  ⨯
• Anne Van den Broeke ,

  Roles Investigation, Methodology, Writing – review & editing

  * E-mail: anne.vandenbroeke@bordet.be (AVdB); david_hill@dfci.harvard.edu (DEH); marc_vidal@dfci.harvard.edu (MV); fdequiedt@uliege.be (FD); jean-claude.twizere@uliege.be (J-CT)

  Affiliations Unit of Animal Genomics, GIGA, Université de Liège (ULiège), Liège, Belgium, Laboratory of Experimental Hematology, Institut Jules Bordet, Université Libre de Bruxelles (ULB), Brussels, Belgium

  ⨯
• David E. Hill ,

  Roles Funding acquisition, Supervision, Writing – review & editing

  * E-mail: anne.vandenbroeke@bordet.be (AVdB); david_hill@dfci.harvard.edu (DEH); marc_vidal@dfci.harvard.edu (MV); fdequiedt@uliege.be (FD); jean-claude.twizere@uliege.be (J-CT)

  Affiliations Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0001-5192-0921

  ⨯
• Marc Vidal ,

  Roles Funding acquisition, Supervision, Writing – review & editing

  * E-mail: anne.vandenbroeke@bordet.be (AVdB); david_hill@dfci.harvard.edu (DEH); marc_vidal@dfci.harvard.edu (MV); fdequiedt@uliege.be (FD); jean-claude.twizere@uliege.be (J-CT)

  Affiliations Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Franck Dequiedt ,

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: anne.vandenbroeke@bordet.be (AVdB); david_hill@dfci.harvard.edu (DEH); marc_vidal@dfci.harvard.edu (MV); fdequiedt@uliege.be (FD); jean-claude.twizere@uliege.be (J-CT)

  Affiliation Laboratory of Gene Expression and Cancer, GIGA Institute, University of Liege, Liege, Belgium

  ⨯
•  [ ... ],
• Jean-Claude Twizere

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: anne.vandenbroeke@bordet.be (AVdB); david_hill@dfci.harvard.edu (DEH); marc_vidal@dfci.harvard.edu (MV); fdequiedt@uliege.be (FD); jean-claude.twizere@uliege.be (J-CT)

  Affiliations Laboratory of Viral Interactomes, GIGA Institute, University of Liege, Liege, Belgium, Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-8683-705X

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