Discovery of re-purposed drugs that slow SARS-CoV-2 replication in human cells

Adam Pickard; Ben C. Calverley; Joan Chang; Richa Garva; Sara Gago; Yinhui Lu; Karl E. Kadler

doi:10.1371/journal.ppat.1009840

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Open Access

Peer-reviewed

Research Article

Discovery of re-purposed drugs that slow SARS-CoV-2 replication in human cells

Adam Pickard ,

Roles Conceptualization, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: adam.pickard@manchester.ac.uk (AP); karl.kadler@manchester.ac.uk (KEK)

Affiliations Wellcome Centre for Cell-Matrix Research, University of Manchester, Oxford Road, Manchester, United Kingdom, School of Biological Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0001-9757-143X

⨯
Ben C. Calverley,

Roles Investigation, Methodology

Affiliations Wellcome Centre for Cell-Matrix Research, University of Manchester, Oxford Road, Manchester, United Kingdom, School of Biological Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0001-9403-0363

⨯
Joan Chang,

Roles Investigation, Methodology

Affiliations Wellcome Centre for Cell-Matrix Research, University of Manchester, Oxford Road, Manchester, United Kingdom, School of Biological Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0002-7283-9759

⨯
Richa Garva,

Roles Investigation

Affiliations Wellcome Centre for Cell-Matrix Research, University of Manchester, Oxford Road, Manchester, United Kingdom, School of Biological Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0001-7752-8936

⨯
Sara Gago,

Roles Investigation, Resources

Affiliation School of Biological Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom
⨯
Yinhui Lu,

Roles Investigation

Affiliations Wellcome Centre for Cell-Matrix Research, University of Manchester, Oxford Road, Manchester, United Kingdom, School of Biological Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom
⨯
Karl E. Kadler

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: adam.pickard@manchester.ac.uk (AP); karl.kadler@manchester.ac.uk (KEK)

Affiliations Wellcome Centre for Cell-Matrix Research, University of Manchester, Oxford Road, Manchester, United Kingdom, School of Biological Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0003-4977-4683

⨯

Discovery of re-purposed drugs that slow SARS-CoV-2 replication in human cells

Adam Pickard,
Ben C. Calverley,
Joan Chang,
Richa Garva,
Sara Gago,
Yinhui Lu,
Karl E. Kadler

Published: September 9, 2021
https://doi.org/10.1371/journal.ppat.1009840

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