Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses

• Sofia Banchenko ,

  Contributed equally to this work with: Sofia Banchenko, Ferdinand Krupp

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – review & editing

  Affiliation Charité–Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Berlin, Germany

  https://orcid.org/0000-0003-2166-1222

  ⨯
• Ferdinand Krupp ,

  Contributed equally to this work with: Sofia Banchenko, Ferdinand Krupp

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Charité–Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Berlin, Germany

  https://orcid.org/0000-0002-0402-8647

  ⨯
• Christine Gotthold,

  Roles Formal analysis, Investigation, Methodology, Resources, Supervision

  Affiliation Charité–Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Berlin, Germany

  ⨯
• Jörg Bürger,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources

  Affiliations Charité–Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Berlin, Germany, Microscopy and Cryo-Electron Microscopy Service Group, Max-Planck-Institute for Molecular Genetics, Berlin, Germany

  ⨯
• Andrea Graziadei,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Visualization, Writing – review & editing

  Affiliation Bioanalytics Unit, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany

  https://orcid.org/0000-0001-7709-6002

  ⨯
• Francis J. O’Reilly,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Visualization

  Affiliation Bioanalytics Unit, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany

  https://orcid.org/0000-0001-9258-0150

  ⨯
• Ludwig Sinn,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software

  Affiliation Bioanalytics Unit, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany

  https://orcid.org/0000-0003-4692-0681

  ⨯
• Olga Ruda,

  Roles Investigation, Methodology

  Affiliation Charité–Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Berlin, Germany

  ⨯
• Juri Rappsilber,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Writing – review & editing

  Affiliations Bioanalytics Unit, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany, Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Christian M. T. Spahn,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Charité–Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Berlin, Germany

  ⨯
• Thorsten Mielke,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Writing – review & editing

  Affiliation Microscopy and Cryo-Electron Microscopy Service Group, Max-Planck-Institute for Molecular Genetics, Berlin, Germany

  https://orcid.org/0000-0001-9275-3146

  ⨯
• Ian A. Taylor,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Macromolecular Structure Laboratory, The Francis Crick Institute, London, United Kingdom

  https://orcid.org/0000-0002-6763-3852

  ⨯
• David Schwefel

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: david.schwefel@charite.de

  Affiliation Charité–Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Berlin, Germany

  https://orcid.org/0000-0002-2945-0908

  ⨯