Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages

Ruth Forman; Larisa Logunova; Hannah Smith; Kelly Wemyss; Iris Mair; Louis Boon; Judith E. Allen; Werner Muller; Joanne L. Pennock; Kathryn J. Else

doi:10.1371/journal.ppat.1009768

Loading metrics

Open Access

Peer-reviewed

Research Article

Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages

Ruth Forman ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

* E-mail: ruth.forman@manchester.ac.uk (RF); Kathryn.else@manchester.ac.uk (KJE)

Affiliation Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0003-0374-6679

⨯
Larisa Logunova,

Roles Investigation, Methodology

Affiliation Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0002-7601-8296

⨯
Hannah Smith,

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0001-8911-9048

⨯
Kelly Wemyss,

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0003-0385-5920

⨯
Iris Mair,

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom
⨯
Louis Boon,

Roles Resources

Affiliation Polpharma Biologics, Utrecht, The Netherlands
⨯
Judith E. Allen,

Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

Affiliation Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0002-3829-066X

⨯
Werner Muller,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliation Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0002-1297-9725

⨯
Joanne L. Pennock,

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliation Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0002-8304-2905

⨯
Kathryn J. Else

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: ruth.forman@manchester.ac.uk (RF); Kathryn.else@manchester.ac.uk (KJE)

Affiliation Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

https://orcid.org/0000-0001-6660-055X

⨯

Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages

Ruth Forman,
Larisa Logunova,
Hannah Smith,
Kelly Wemyss,
Iris Mair,
Louis Boon,
Judith E. Allen,
Werner Muller,
Joanne L. Pennock,
Kathryn J. Else

Published: July 30, 2021
https://doi.org/10.1371/journal.ppat.1009768

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
Colon
Is the Subject Area "Colon" applicable to this article?

Thanks for your feedback.
Gastrointestinal tract
Is the Subject Area "Gastrointestinal tract" applicable to this article?

Thanks for your feedback.
Monocytes
Is the Subject Area "Monocytes" applicable to this article?

Thanks for your feedback.
Eggs
Is the Subject Area "Eggs" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Parasitic diseases
Is the Subject Area "Parasitic diseases" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.