Phosphatidylserine receptors enhance SARS-CoV-2 infection

Dana Bohan; Hanora Van Ert; Natalie Ruggio; Kai J. Rogers; Mohammad Badreddine; José A. Aguilar Briseño; Jonah M. Elliff; Roberth Anthony Rojas Chavez; Boning Gao; Tomasz Stokowy; Eleni Christakou; Petri Kursula; David Micklem; Gro Gausdal; Hillel Haim; John Minna; James B. Lorens; Wendy Maury

doi:10.1371/journal.ppat.1009743

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Peer-reviewed

Research Article

Phosphatidylserine receptors enhance SARS-CoV-2 infection

Dana Bohan ,

Contributed equally to this work with: Dana Bohan, Hanora Van Ert

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

https://orcid.org/0000-0002-9239-3053

⨯
Hanora Van Ert ,

Contributed equally to this work with: Dana Bohan, Hanora Van Ert

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

https://orcid.org/0000-0002-3259-1912

⨯
Natalie Ruggio,

Roles Formal analysis, Investigation

Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

https://orcid.org/0000-0002-9696-2233

⨯
Kai J. Rogers,

Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America
⨯
Mohammad Badreddine,

Roles Investigation

Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America
⨯
José A. Aguilar Briseño,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

https://orcid.org/0000-0002-7293-4027

⨯
Jonah M. Elliff,

Roles Investigation

Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America
⨯
Roberth Anthony Rojas Chavez,

Roles Investigation

Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

https://orcid.org/0000-0002-7023-2718

⨯
Boning Gao,

Roles Resources

Affiliation Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Tomasz Stokowy,

Roles Data curation, Formal analysis, Software

Affiliation Department of Biomedicine, University of Bergen, Bergen, Norway
⨯
Eleni Christakou,

Roles Investigation

Affiliations Department of Biomedicine, University of Bergen, Bergen, Norway, BerGenBio ASA, Bergen, Norway
⨯
Petri Kursula,

Roles Investigation, Methodology, Resources

Affiliations Department of Biomedicine, University of Bergen, Bergen, Norway, Biocenter Oulu & Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland

https://orcid.org/0000-0001-8529-3751

⨯
David Micklem,

Roles Formal analysis, Investigation, Methodology, Resources

Affiliation BerGenBio ASA, Bergen, Norway

https://orcid.org/0000-0003-2756-2591

⨯
Gro Gausdal,

Roles Resources

Affiliation BerGenBio ASA, Bergen, Norway
⨯
Hillel Haim,

Roles Formal analysis, Investigation, Methodology, Resources

Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

https://orcid.org/0000-0002-6071-5089

⨯
John Minna,

Roles Conceptualization, Resources

Affiliation Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

https://orcid.org/0000-0002-7776-0767

⨯
James B. Lorens,

Roles Conceptualization, Methodology, Resources, Supervision

Affiliation Department of Biomedicine, University of Bergen, Bergen, Norway

https://orcid.org/0000-0002-6782-3349

⨯
[ ... ],
Wendy Maury

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: wendy-maury@uiowa.edu

Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

https://orcid.org/0000-0002-9892-4484

⨯
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Phosphatidylserine receptors enhance SARS-CoV-2 infection

Dana Bohan,
Hanora Van Ert,
Natalie Ruggio,
Kai J. Rogers,
Mohammad Badreddine,
José A. Aguilar Briseño,
Jonah M. Elliff,
Roberth Anthony Rojas Chavez,
Boning Gao,
Tomasz Stokowy

Published: November 19, 2021
https://doi.org/10.1371/journal.ppat.1009743

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