Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates

• Jelle van Schooten ,

  Contributed equally to this work with: Jelle van Schooten, Marlies M. van Haaren

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands

  https://orcid.org/0000-0002-5202-355X

  ⨯
• Marlies M. van Haaren ,

  Contributed equally to this work with: Jelle van Schooten, Marlies M. van Haaren

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands

  https://orcid.org/0000-0003-3636-6410

  ⨯
• Hui Li,

  Roles Resources

  Affiliation Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  ⨯
• Laura E. McCoy,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliations Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America, Division of Infection and Immunity, University College London, London, United Kingdom

  https://orcid.org/0000-0001-9503-7946

  ⨯
• Colin Havenar-Daughton,

  Roles Investigation, Methodology, Resources

  Affiliation Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America

  https://orcid.org/0000-0002-2880-3927

  ⨯
• Christopher A. Cottrell,

  Roles Investigation

  Affiliation Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America

  https://orcid.org/0000-0002-3364-3083

  ⨯
• Judith A. Burger,

  Roles Investigation

  Affiliation Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands

  https://orcid.org/0000-0002-7311-9921

  ⨯
• Patricia van der Woude,

  Roles Investigation

  Affiliation Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands

  ⨯
• Leanne C. Helgers,

  Roles Investigation

  Affiliation Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands

  ⨯
• Ilhan Tomris,

  Roles Investigation

  Affiliation Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands

  ⨯
• Celia C. Labranche,

  Roles Investigation

  Affiliation Laboratory for AIDS Vaccine Research and Development, Duke University Medical Center, Durham, North Carolina, United States of America

  ⨯
• David C. Montefiori,

  Roles Funding acquisition, Supervision

  Affiliation Laboratory for AIDS Vaccine Research and Development, Duke University Medical Center, Durham, North Carolina, United States of America

  ⨯
• Andrew B. Ward,

  Roles Funding acquisition, Supervision

  Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, International AIDS Vaccine Initiative—Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, California, United States of America, Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, California, United States of America

  https://orcid.org/0000-0001-7153-3769

  ⨯
• Dennis R. Burton,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliations Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America, International AIDS Vaccine Initiative—Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, California, United States of America, Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, California, United States of America, Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

  ⨯
• John P. Moore,

  Roles Funding acquisition, Resources, Supervision

  Affiliation Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America

  https://orcid.org/0000-0002-9902-6096

  ⨯
• Rogier W. Sanders,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands, Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America

  https://orcid.org/0000-0002-2324-8573

  ⨯
• Shane Crotty,

  Roles Funding acquisition, Resources, Supervision

  Affiliation Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America

  ⨯
• George M. Shaw,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

  ⨯
•  [ ... ],
• Marit J. van Gils

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: M.J.vangils@amsterdamumc.nl

  Affiliation Department of Medical Microbiology, Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands

  https://orcid.org/0000-0003-3422-8161

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