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Open Access
Peer-reviewed
Research Article
SARS-CoV-2 infection in the Syrian hamster model causes inflammation as well as type I interferon dysregulation in both respiratory and non-respiratory tissues including the heart and kidney
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Magen Ellen Francis,
Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing
Affiliations Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Una Goncin,
Roles Formal analysis, Investigation
Affiliation Department of Medical Imaging, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Andrea Kroeker,
Roles Formal analysis, Investigation
Affiliation Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Cynthia Swan,
Roles Formal analysis, Investigation
Affiliation Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Robyn Ralph,
Roles Investigation
Affiliations Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Yao Lu,
Roles Investigation
Affiliation Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Athema Louise Etzioni,
Roles Formal analysis
Affiliation Department of Pathobiology, Tuskegee University College of Veterinary Medicine, Tuskegee Institute, Tuskegee, Alabama, United States of America
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Darryl Falzarano,
Roles Formal analysis
Affiliations Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Volker Gerdts,
Roles Conceptualization, Writing – original draft
Affiliation Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Steven Machtaler,
Roles Formal analysis, Investigation
Affiliation Department of Medical Imaging, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Jason Kindrachuk,
Roles Conceptualization, Investigation
Affiliations Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, Laboratory of Emerging and Re-Emerging Viruses, Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada
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Alyson Ann Kelvin
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing
* E-mail: alyson.kelvin@usask.ca
Affiliations Vaccine and Infectious Disease Organization VIDO, University of Saskatchewan, Saskatoon, Saskatchewan, Canada, Department of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada, Department of Pediatrics, Division of Infectious Disease, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada, Canadian Centre for Vaccinology, IWK Health Centre, Halifax, Nova Scotia, Canada
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SARS-CoV-2 infection in the Syrian hamster model causes inflammation as well as type I interferon dysregulation in both respiratory and non-respiratory tissues including the heart and kidney
- Magen Ellen Francis,
- Una Goncin,
- Andrea Kroeker,
- Cynthia Swan,
- Robyn Ralph,
- Yao Lu,
- Athema Louise Etzioni,
- Darryl Falzarano,
- Volker Gerdts,
- Steven Machtaler
- Published: July 15, 2021
- https://doi.org/10.1371/journal.ppat.1009705