Early treatment with a combination of two potent neutralizing antibodies improves clinical outcomes and reduces virus replication and lung inflammation in SARS-CoV-2 infected macaques

• Koen K. A. Van Rompay ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: kkvanrompay@ucdavis.edu (KKAVR); nussen@rockefeller.edu (MCN); rreader@ucdavis.edu (JRR)

  Affiliations California National Primate Research Center, University of California, Davis, United States of America, Department of Pathology, Microbiology and Immunology, University of California, Davis, California, United States of America

  https://orcid.org/0000-0002-7375-1337

  ⨯
• Katherine J. Olstad,

  Roles Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations California National Primate Research Center, University of California, Davis, United States of America, Department of Pathology, Microbiology and Immunology, University of California, Davis, California, United States of America

  ⨯
• Rebecca L. Sammak,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation California National Primate Research Center, University of California, Davis, United States of America

  https://orcid.org/0000-0003-3271-0413

  ⨯
• Joseph Dutra,

  Roles Investigation, Methodology, Validation

  Affiliation Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, California, United States of America

  https://orcid.org/0000-0002-5553-5200

  ⨯
• Jennifer K. Watanabe,

  Roles Investigation

  Affiliation California National Primate Research Center, University of California, Davis, United States of America

  ⨯
• Jodie L. Usachenko,

  Roles Investigation

  Affiliation California National Primate Research Center, University of California, Davis, United States of America

  ⨯
• Ramya Immareddy,

  Roles Investigation

  Affiliation California National Primate Research Center, University of California, Davis, United States of America

  ⨯
• Anil Verma,

  Roles Investigation

  Affiliation Center for Immunology and Infectious Diseases, University of California, Davis, California, United States of America

  ⨯
• Yashavanth Shaan Lakshmanappa,

  Roles Investigation

  Affiliation Center for Immunology and Infectious Diseases, University of California, Davis, California, United States of America

  https://orcid.org/0000-0002-7794-1963

  ⨯
• Brian A. Schmidt,

  Roles Investigation

  Affiliation Center for Immunology and Infectious Diseases, University of California, Davis, California, United States of America

  https://orcid.org/0000-0002-3405-4862

  ⨯
• Jamin W. Roh,

  Roles Investigation

  Affiliation Center for Immunology and Infectious Diseases, University of California, Davis, California, United States of America

  ⨯
• Sonny R. Elizaldi,

  Roles Investigation

  Affiliation Center for Immunology and Infectious Diseases, University of California, Davis, California, United States of America

  https://orcid.org/0000-0001-7464-8721

  ⨯
• A. Mark Allen,

  Roles Investigation

  Affiliation California National Primate Research Center, University of California, Davis, United States of America

  ⨯
• Frauke Muecksch,

  Roles Investigation

  Affiliation Laboratory of Retrovirology, The Rockefeller University, New York, New York, United States of America

  https://orcid.org/0000-0002-0132-5101

  ⨯
• Julio C. C. Lorenzi,

  Roles Investigation

  Affiliation Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, United States of America

  https://orcid.org/0000-0003-2492-3961

  ⨯
• Sarah Lockwood,

  Roles Investigation, Visualization

  Affiliation California National Primate Research Center, University of California, Davis, United States of America

  ⨯
• Rachel E. Pollard,

  Roles Formal analysis

  Affiliation School of Veterinary Medicine, University of California, Davis, California, United States of America

  https://orcid.org/0000-0003-2986-1827

  ⨯
• JoAnn L. Yee,

  Roles Investigation

  Affiliation California National Primate Research Center, University of California, Davis, United States of America

  https://orcid.org/0000-0002-5514-9836

  ⨯
• Peter B. Nham,

  Roles Investigation

  Affiliation California National Primate Research Center, University of California, Davis, United States of America

  ⨯
• Amir Ardeshir,

  Roles Formal analysis

  Affiliation California National Primate Research Center, University of California, Davis, United States of America

  https://orcid.org/0000-0002-4330-4659

  ⨯
• Jesse D. Deere,

  Roles Investigation

  Affiliation Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, California, United States of America

  https://orcid.org/0000-0002-2539-0338

  ⨯
• Jean Patterson,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation Translational Research Section, Virology Branch, DMID/NIAID/NIH, Rockville, Maryland, United States of America

  ⨯
• Que Dang,

  Roles Conceptualization, Writing – review & editing

  Affiliation Preclinical Research and Development Branch, Vaccine Research Program, DAIDS/NIAID/NIH, Rockville, Maryland, United States of America

  ⨯
• Theodora Hatziioannou,

  Roles Investigation, Validation

  Affiliation Laboratory of Retrovirology, The Rockefeller University, New York, New York, United States of America

  https://orcid.org/0000-0002-7889-0766

  ⨯
• Paul D. Bieniasz,

  Roles Investigation, Validation

  Affiliations Laboratory of Retrovirology, The Rockefeller University, New York, New York, United States of America, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, United States of America

  https://orcid.org/0000-0002-2368-3719

  ⨯
• Smita S. Iyer,

  Roles Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations California National Primate Research Center, University of California, Davis, United States of America, Department of Pathology, Microbiology and Immunology, University of California, Davis, California, United States of America, Center for Immunology and Infectious Diseases, University of California, Davis, California, United States of America

  https://orcid.org/0000-0002-8918-7005

  ⨯
• Dennis J. Hartigan-O’Connor,

  Roles Methodology, Writing – review & editing

  Affiliations California National Primate Research Center, University of California, Davis, United States of America, Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, California, United States of America

  https://orcid.org/0000-0003-4822-636X

  ⨯
• Michel C. Nussenzweig ,

  Roles Conceptualization, Formal analysis, Writing – review & editing

  * E-mail: kkvanrompay@ucdavis.edu (KKAVR); nussen@rockefeller.edu (MCN); rreader@ucdavis.edu (JRR)

  Affiliations Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, United States of America, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, United States of America

  ⨯
•  [ ... ],
• J. Rachel Reader

  Roles Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: kkvanrompay@ucdavis.edu (KKAVR); nussen@rockefeller.edu (MCN); rreader@ucdavis.edu (JRR)

  Affiliations California National Primate Research Center, University of California, Davis, United States of America, Department of Pathology, Microbiology and Immunology, University of California, Davis, California, United States of America

  https://orcid.org/0000-0003-3864-6731

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