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Open Access
Peer-reviewed
Research Article
Rapid, reliable, and reproducible cell fusion assay to quantify SARS-Cov-2 spike interaction with hACE2
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Min Zhao,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing
Affiliation Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, United States of America
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Pei-Yi Su,
Roles Investigation, Validation
Affiliation Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, United States of America
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Danielle A. Castro,
Roles Investigation, Validation
Affiliation Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, United States of America
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Therese N. Tripler,
Roles Resources
Affiliation Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, Connecticut, United States of America
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Yingxia Hu,
Roles Resources
Affiliation Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, Connecticut, United States of America
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Matthew Cook,
Roles Resources
Affiliation Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, Connecticut, United States of America
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Albert I. Ko,
Roles Resources
Affiliations Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, United States of America, Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, United States of America
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Shelli F. Farhadian,
Roles Resources
Affiliation Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, United States of America
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Benjamin Israelow,
Roles Investigation, Validation
Affiliation Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, United States of America
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Charles S. Dela Cruz,
Roles Investigation, Resources
Affiliation Department of Internal Medicine, Section of Pulmonary and Critical Care Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America
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Yong Xiong,
Roles Resources
Affiliation Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, Connecticut, United States of America
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Richard E. Sutton ,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: richard.sutton@yale.edu
Affiliation Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut, United States of America
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the Yale IMPACT Research Team
¶Membership list of Yale IMPACT Research Team is provided in the acknowledgments
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Rapid, reliable, and reproducible cell fusion assay to quantify SARS-Cov-2 spike interaction with hACE2
- Min Zhao,
- Pei-Yi Su,
- Danielle A. Castro,
- Therese N. Tripler,
- Yingxia Hu,
- Matthew Cook,
- Albert I. Ko,
- Shelli F. Farhadian,
- Benjamin Israelow,
- Charles S. Dela Cruz
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- Published: June 24, 2021
- https://doi.org/10.1371/journal.ppat.1009683