Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection

• Michelle Y.-H. Lee ,

  Contributed equally to this work with: Michelle Y.-H. Lee, Amit A. Upadhyay, Hasse Walum, Reem A. Dawoud, Christine Grech

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0002-5722-1109

  ⨯
• Amit A. Upadhyay ,

  Contributed equally to this work with: Michelle Y.-H. Lee, Amit A. Upadhyay, Hasse Walum, Reem A. Dawoud, Christine Grech

  Roles Conceptualization, Data curation, Formal analysis, Writing – original draft

  Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0002-0952-4164

  ⨯
• Hasse Walum ,

  Contributed equally to this work with: Michelle Y.-H. Lee, Amit A. Upadhyay, Hasse Walum, Reem A. Dawoud, Christine Grech

  Roles Conceptualization, Formal analysis, Writing – original draft

  Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America

  ⨯
• Chi N. Chan,

  Roles Formal analysis, Investigation, Methodology, Validation

  Affiliation Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America

  https://orcid.org/0000-0001-9106-9481

  ⨯
• Reem A. Dawoud ,

  Contributed equally to this work with: Michelle Y.-H. Lee, Amit A. Upadhyay, Hasse Walum, Reem A. Dawoud, Christine Grech

  Roles Methodology, Project administration

  Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0003-4857-505X

  ⨯
• Christine Grech ,

  Contributed equally to this work with: Michelle Y.-H. Lee, Amit A. Upadhyay, Hasse Walum, Reem A. Dawoud, Christine Grech

  Roles Methodology

  Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0002-0737-2048

  ⨯
• Justin L. Harper,

  Roles Methodology

  Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0002-6948-3501

  ⨯
• Kirti A. Karunakaran,

  Roles Methodology

  Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0002-3310-7686

  ⨯
• Sydney A. Nelson,

  Roles Investigation

  Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America

  ⨯
• Ernestine A. Mahar,

  Roles Investigation, Project administration

  Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0002-6740-0688

  ⨯
• Kyndal L. Goss,

  Roles Formal analysis

  Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0002-0863-9998

  ⨯
• Diane G. Carnathan,

  Roles Investigation

  Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America

  ⨯
• Barbara Cervasi,

  Roles Investigation, Methodology

  Affiliation Flow Cytometry Core, Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America

  ⨯
• Kiran Gill,

  Roles Investigation, Methodology

  Affiliation Flow Cytometry Core, Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America

  ⨯
• Gregory K. Tharp,

  Roles Data curation, Formal analysis

  Affiliation Yerkes NHP Genomics Core Laboratory, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0003-3075-755X

  ⨯
• Elizabeth R. Wonderlich,

  Roles Investigation, Methodology

  Affiliation Southern Research, Frederick, Maryland, United States of America

  https://orcid.org/0000-0002-0773-6569

  ⨯
• Vijayakumar Velu,

  Roles Formal analysis, Investigation

  Affiliations Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America, Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0003-4238-1924

  ⨯
• Simon M. Barratt-Boyes,

  Roles Resources

  Affiliation Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

  ⨯
• Mirko Paiardini,

  Roles Resources

  Affiliations Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America, Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia, United States of America

  ⨯
• Guido Silvestri,

  Roles Resources

  Affiliations Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America, Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia, United States of America

  ⨯
• Jacob D. Estes,

  Roles Formal analysis, Resources

  Affiliations Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America

  https://orcid.org/0000-0002-9652-6394

  ⨯
•  [ ... ],
• Steven E. Bosinger

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: sbosing@emory.edu

  Affiliations Division of Microbiology & Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America, Yerkes NHP Genomics Core Laboratory, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America, Department of Pathology and Laboratory Medicine, School of Medicine, Emory University, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0002-2116-5061

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