A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site

• Tatsuya Maehigashi ,

  Contributed equally to this work with: Tatsuya Maehigashi, Seohyun Ahn, Uk-Il Kim, Jared Lindenberger, Adrian Oo

  Roles Data curation, Formal analysis, Validation

  Affiliation Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0002-9639-2250

  ⨯
• Seohyun Ahn ,

  Contributed equally to this work with: Tatsuya Maehigashi, Seohyun Ahn, Uk-Il Kim, Jared Lindenberger, Adrian Oo

  Roles Data curation, Formal analysis, Methodology, Validation, Writing – review & editing

  Affiliation ST Pharm Co., Ltd., Seoul, South Korea

  https://orcid.org/0000-0003-4899-975X

  ⨯
• Uk-Il Kim ,

  Contributed equally to this work with: Tatsuya Maehigashi, Seohyun Ahn, Uk-Il Kim, Jared Lindenberger, Adrian Oo

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation ST Pharm Co., Ltd., Seoul, South Korea

  ⨯
• Jared Lindenberger ,

  Contributed equally to this work with: Tatsuya Maehigashi, Seohyun Ahn, Uk-Il Kim, Jared Lindenberger, Adrian Oo

  Roles Data curation, Formal analysis

  Affiliation Division of Infectious Diseases, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America

  ⨯
• Adrian Oo ,

  Contributed equally to this work with: Tatsuya Maehigashi, Seohyun Ahn, Uk-Il Kim, Jared Lindenberger, Adrian Oo

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0002-2469-5391

  ⨯
• Pratibha C. Koneru,

  Roles Data curation, Formal analysis

  Affiliation Division of Infectious Diseases, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America

  ⨯
• Bijan Mahboubi,

  Roles Data curation, Formal analysis

  Affiliation Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia, United States of America

  ⨯
• Alan N. Engelman,

  Roles Methodology, Resources

  Affiliations Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-9709-2591

  ⨯
• Mamuka Kvaratskhelia ,

  Roles Funding acquisition, Investigation, Supervision, Writing – review & editing

  * E-mail: mamuka.kvaratskhelia@cuanschutz.edu(MK); kyungjin.kim@stpharm.co.kr(KK); baek.kim@emory.edu (BK)

  Affiliation Division of Infectious Diseases, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America

  ⨯
• Kyungjin Kim ,

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – review & editing

  * E-mail: mamuka.kvaratskhelia@cuanschutz.edu(MK); kyungjin.kim@stpharm.co.kr(KK); baek.kim@emory.edu (BK)

  Affiliation ST Pharm Co., Ltd., Seoul, South Korea

  https://orcid.org/0000-0002-8271-7640

  ⨯
• Baek Kim

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft

  * E-mail: mamuka.kvaratskhelia@cuanschutz.edu(MK); kyungjin.kim@stpharm.co.kr(KK); baek.kim@emory.edu (BK)

  Affiliations Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia, United States of America, Center for Drug Discovery, Children’s Healthcare of Atlanta, Atlanta, Georgia, United States of America

  https://orcid.org/0000-0001-7986-4335

  ⨯