A plasmid locus associated with Klebsiella clinical infections encodes a microbiome-dependent gut fitness factor

• Jay Vornhagen,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Pathology, University of Michigan, Ann Arbor, MI, United States of America, Department of Microbiology & Immunology, University of Michigan, Ann Arbor, MI, United States of America

  https://orcid.org/0000-0002-1685-302X

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• Christine M. Bassis,

  Roles Data curation, Formal analysis, Visualization, Writing – review & editing

  Affiliation Department of Internal Medicine/Infectious Diseases Division, University of Michigan, Ann Arbor, MI, United States of America

  https://orcid.org/0000-0001-6047-0678

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• Srividya Ramakrishnan,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Computer Science, Johns Hopkins University, Baltimore, MD, United States of America

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• Robert Hein,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Internal Medicine/Infectious Diseases Division, University of Michigan, Ann Arbor, MI, United States of America

  https://orcid.org/0000-0001-8670-0160

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• Sophia Mason,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Pathology, University of Michigan, Ann Arbor, MI, United States of America

  https://orcid.org/0000-0003-4030-508X

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• Yehudit Bergman,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

  https://orcid.org/0000-0002-4262-7173

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• Nicole Sunshine,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Pathology, University of Michigan, Ann Arbor, MI, United States of America

  https://orcid.org/0000-0002-4197-7913

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• Yunfan Fan,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States of America

  https://orcid.org/0000-0002-3765-5313

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• Caitlyn L. Holmes,

  Roles Writing – review & editing

  Affiliations Department of Pathology, University of Michigan, Ann Arbor, MI, United States of America, Department of Microbiology & Immunology, University of Michigan, Ann Arbor, MI, United States of America

  https://orcid.org/0000-0001-5818-148X

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• Winston Timp,

  Roles Formal analysis, Supervision, Writing – review & editing

  Affiliations Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States of America, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America, Department of Medicine, Division of Infectious Disease, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

  https://orcid.org/0000-0003-2083-6027

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• Michael C. Schatz,

  Roles Formal analysis, Supervision, Writing – review & editing

  Affiliations Department of Computer Science, Johns Hopkins University, Baltimore, MD, United States of America, Department of Biology, Johns Hopkins University, Baltimore, MD, United States of America, Simons Center for Quantitative Biology, Cold Spring Harbor, NY, United States of America

  https://orcid.org/0000-0002-4118-4446

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• Vincent B. Young,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliations Department of Microbiology & Immunology, University of Michigan, Ann Arbor, MI, United States of America, Department of Internal Medicine/Infectious Diseases Division, University of Michigan, Ann Arbor, MI, United States of America

  https://orcid.org/0000-0003-3687-2364

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• Patricia J. Simner,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliation Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

  https://orcid.org/0000-0001-6134-151X

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• Michael A. Bachman

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: mikebach@med.umich.edu

  Affiliations Department of Pathology, University of Michigan, Ann Arbor, MI, United States of America, Department of Microbiology & Immunology, University of Michigan, Ann Arbor, MI, United States of America

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