Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model

• Leo Y Lee,

  Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Current address: Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Australia

  Affiliation WHO Collaborating Centre for Reference and Research on Influenza, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia

  https://orcid.org/0000-0001-6704-1235

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• Jie Zhou,

  Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Infectious Disease, Imperial College London, London, United Kingdom

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• Paulina Koszalka,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations WHO Collaborating Centre for Reference and Research on Influenza, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia, Biomedicine Discovery Institute & Department of Microbiology, Monash University, Victoria, Australia

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• Rebecca Frise,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Infectious Disease, Imperial College London, London, United Kingdom

  https://orcid.org/0000-0002-5522-623X

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• Rubaiyea Farrukee,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Australia

  https://orcid.org/0000-0001-9023-246X

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• Keiko Baba,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Shionogi & Co., Ltd, Osaka, Japan

  https://orcid.org/0000-0001-8463-2897

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• Shahjahan Miah,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Public Health England, London, United Kingdom

  https://orcid.org/0000-0001-7810-3497

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• Takao Shishido,

  Roles Methodology, Supervision, Writing – review & editing

  Affiliation Shionogi & Co., Ltd, Osaka, Japan

  https://orcid.org/0000-0002-2549-0945

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• Monica Galiano,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Francis Crick Institute, London, United Kingdom

  https://orcid.org/0000-0001-7046-3762

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• Takashi Hashimoto,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Shionogi & Co., Ltd, Osaka, Japan

  https://orcid.org/0000-0002-6171-2787

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• Shinya Omoto,

  Roles Methodology, Supervision, Writing – review & editing

  Affiliation Shionogi & Co., Ltd, Osaka, Japan

  https://orcid.org/0000-0002-2730-3912

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• Takeki Uehara,

  Roles Supervision, Writing – review & editing

  Affiliation Shionogi & Co., Ltd, Osaka, Japan

  https://orcid.org/0000-0002-5853-9426

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• Edin J. Mifsud,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations WHO Collaborating Centre for Reference and Research on Influenza, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia, Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Australia

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• Neil Collinson,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation Roche Products Ltd, Welwyn Garden City, United Kingdom

  https://orcid.org/0000-0001-6602-7845

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• Klaus Kuhlbusch,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation F. Hoffmann-La Roche Ltd, Basel, Switzerland

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• Barry Clinch,

  Roles Conceptualization, Writing – review & editing

  Affiliation Roche Products Ltd, Welwyn Garden City, United Kingdom

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• Steffen Wildum,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  Affiliation F. Hoffmann-La Roche Ltd, Basel, Switzerland

  https://orcid.org/0000-0001-9779-5740

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• Wendy S. Barclay,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Infectious Disease, Imperial College London, London, United Kingdom

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•  [ ... ],
• Aeron C. Hurt

  Roles Conceptualization, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: aeron.hurt@roche.com

  Affiliations WHO Collaborating Centre for Reference and Research on Influenza, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia, Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Australia, F. Hoffmann-La Roche Ltd, Basel, Switzerland

  https://orcid.org/0000-0001-9731-3481

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