Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2

• Huihui Mou ,

  Contributed equally to this work with: Huihui Mou, Brian D. Quinlan, Haiyong Peng

  Roles Conceptualization, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  https://orcid.org/0000-0001-7358-368X

  ⨯
• Brian D. Quinlan ,

  Contributed equally to this work with: Huihui Mou, Brian D. Quinlan, Haiyong Peng

  Roles Investigation

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  ⨯
• Haiyong Peng ,

  Contributed equally to this work with: Huihui Mou, Brian D. Quinlan, Haiyong Peng

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  https://orcid.org/0000-0003-0312-1337

  ⨯
• Guanqun Liu,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Florida Research and Innovation Center, Cleveland Clinic, Port Saint Lucie, FL, United States of America

  https://orcid.org/0000-0003-2520-7625

  ⨯
• Yan Guo,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  ⨯
• Shoujiao Peng,

  Roles Investigation

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  ⨯
• Lizhou Zhang,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  ⨯
• Meredith E. Davis-Gardner,

  Roles Methodology, Writing – review & editing

  Current address: Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  https://orcid.org/0000-0002-6133-3613

  ⨯
• Matthew R. Gardner,

  Roles Methodology, Resources, Writing – review & editing

  Current address: Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  ⨯
• Gogce Crynen,

  Roles Software

  Affiliation Bioinformatics and Statistics Core, The Scripps Research Institute, Jupiter, FL, United States of America

  https://orcid.org/0000-0001-6066-9900

  ⨯
• Lindsey B. DeVaux,

  Roles Investigation

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  https://orcid.org/0000-0002-9064-5325

  ⨯
• Zhi Xiang Voo,

  Roles Investigation

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  ⨯
• Charles C. Bailey,

  Roles Resources

  Affiliation Emmune, Inc., Juno Beach, FL, United States of America

  https://orcid.org/0000-0003-0200-3523

  ⨯
• Michael D. Alpert,

  Roles Resources

  Affiliation Emmune, Inc., Juno Beach, FL, United States of America

  https://orcid.org/0000-0002-4056-9707

  ⨯
• Christoph Rader ,

  Roles Supervision

  * E-mail: crader@scripps.edu (CR); gackm@ccf.org (MUG); hchoe@scripps.edu (HC); mfarzan@scripps.edu (MF)

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  https://orcid.org/0000-0001-9955-3454

  ⨯
• Michaela U. Gack ,

  Roles Supervision

  * E-mail: crader@scripps.edu (CR); gackm@ccf.org (MUG); hchoe@scripps.edu (HC); mfarzan@scripps.edu (MF)

  Affiliation Florida Research and Innovation Center, Cleveland Clinic, Port Saint Lucie, FL, United States of America

  https://orcid.org/0000-0002-2163-2598

  ⨯
• Hyeryun Choe ,

  Roles Supervision

  * E-mail: crader@scripps.edu (CR); gackm@ccf.org (MUG); hchoe@scripps.edu (HC); mfarzan@scripps.edu (MF)

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  ⨯
•  [ ... ],
• Michael Farzan

  Roles Conceptualization, Funding acquisition, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: crader@scripps.edu (CR); gackm@ccf.org (MUG); hchoe@scripps.edu (HC); mfarzan@scripps.edu (MF)

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, United States of America

  https://orcid.org/0000-0002-2990-5319

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