The multi-functional reovirus σ3 protein is a virulence factor that suppresses stress granule formation and is associated with myocardial injury

• Yingying Guo,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

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• Meleana M. Hinchman,

  Roles Investigation, Methodology

  Affiliation Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

  https://orcid.org/0000-0002-7642-9458

  ⨯
• Mercedes Lewandrowski,

  Roles Data curation, Investigation

  Affiliation Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

  https://orcid.org/0000-0003-2613-8860

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• Shaun T. Cross,

  Roles Data curation, Formal analysis, Investigation, Software, Writing – review & editing

  Affiliations Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America, Cornell Institute of Host-Microbe Interactions and Disease, Cornell University, Ithaca, New York, United States of America

  https://orcid.org/0000-0003-0846-1488

  ⨯
• Danica M. Sutherland,

  Roles Formal analysis, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliation Departments of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0001-9328-4994

  ⨯
• Olivia L. Welsh,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Departments of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0002-8039-7807

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• Terence S. Dermody,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Departments of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Departments of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Institute of Infection, Inflammation, and Immunity, UPMC Children’s Hospital of Pittsburgh, Pennsylvania, United States of America

  https://orcid.org/0000-0003-1853-8741

  ⨯
• John S. L. Parker

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: jsp7@cornell.edu

  Affiliations Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America, Cornell Institute of Host-Microbe Interactions and Disease, Cornell University, Ithaca, New York, United States of America

  https://orcid.org/0000-0003-4487-4175

  ⨯