Targeted mutagenesis on PDGFRα-Fc identifies amino acid modifications that allow efficient inhibition of HCMV infection while abolishing PDGF sequestration

• Svenja Feldmann,

  Roles Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Institute of Virology, Ulm University Medical Center, Ulm, Germany

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• Immanuel Grimm,

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation AiCuris Anti-infective Cures GmbH, Wuppertal, Germany

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• Dagmar Stöhr,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Institute of Virology, Ulm University Medical Center, Ulm, Germany

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• Chiara Antonini,

  Roles Investigation, Validation, Writing – review & editing

  Affiliations Institute of Virology, Ulm University Medical Center, Ulm, Germany, Department of Molecular Medicine, University of Padua, Padua, Italy

  https://orcid.org/0000-0002-3993-3516

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• Peter Lischka,

  Roles Conceptualization, Project administration, Supervision, Validation, Writing – review & editing

  Affiliation AiCuris Anti-infective Cures GmbH, Wuppertal, Germany

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• Christian Sinzger ,

  Contributed equally to this work with: Christian Sinzger, Cora Stegmann

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – review & editing

  * E-mail: christian.sinzger@uniklinik-ulm.de (CSi); cora.stegmann@posteo.de (CSt)

  Affiliation Institute of Virology, Ulm University Medical Center, Ulm, Germany

  https://orcid.org/0000-0002-9282-1783

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• Cora Stegmann

  Contributed equally to this work with: Christian Sinzger, Cora Stegmann

  Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: christian.sinzger@uniklinik-ulm.de (CSi); cora.stegmann@posteo.de (CSt)

  Current address: Division of Biological Sciences, University of Montana, Missoula, Montana, United States of America

  Affiliation Institute of Virology, Ulm University Medical Center, Ulm, Germany

  https://orcid.org/0000-0003-4408-4026

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