Intranasal type I interferon treatment is beneficial only when administered before clinical signs onset in the SARS-CoV-2 hamster model

• Pierre Bessière,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Ecole nationale vétérinaire de Toulouse, ENVT, INRAE, UMR 1225, IHAP, Université de Toulouse, Toulouse, France

  https://orcid.org/0000-0001-5657-0027

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• Marine Wasniewski ,

  Contributed equally to this work with: Marine Wasniewski, Evelyne Picard-Meyer, Alexandre Servat

  Roles Investigation, Methodology

  Affiliation Nancy laboratory for rabies and wildlife, ANSES, Lyssavirus Unit, Malzéville, France

  https://orcid.org/0000-0001-5054-3634

  ⨯
• Evelyne Picard-Meyer ,

  Contributed equally to this work with: Marine Wasniewski, Evelyne Picard-Meyer, Alexandre Servat

  Roles Investigation, Methodology

  Affiliation Nancy laboratory for rabies and wildlife, ANSES, Lyssavirus Unit, Malzéville, France

  https://orcid.org/0000-0001-9122-9027

  ⨯
• Alexandre Servat ,

  Contributed equally to this work with: Marine Wasniewski, Evelyne Picard-Meyer, Alexandre Servat

  Roles Investigation, Methodology

  Affiliation Nancy laboratory for rabies and wildlife, ANSES, Lyssavirus Unit, Malzéville, France

  https://orcid.org/0000-0003-4753-6614

  ⨯
• Thomas Figueroa,

  Roles Investigation, Methodology

  Affiliation Ecole nationale vétérinaire de Toulouse, ENVT, INRAE, UMR 1225, IHAP, Université de Toulouse, Toulouse, France

  https://orcid.org/0000-0002-4141-271X

  ⨯
• Charlotte Foret-Lucas,

  Roles Investigation, Methodology

  Affiliation Ecole nationale vétérinaire de Toulouse, ENVT, INRAE, UMR 1225, IHAP, Université de Toulouse, Toulouse, France

  ⨯
• Amelia Coggon,

  Roles Investigation, Methodology

  Affiliation Ecole nationale vétérinaire de Toulouse, ENVT, INRAE, UMR 1225, IHAP, Université de Toulouse, Toulouse, France

  https://orcid.org/0000-0001-9543-7317

  ⨯
• Sandrine Lesellier,

  Roles Investigation, Methodology

  Affiliation Nancy laboratory for rabies and wildlife, ANSES, Atton experimental facility, Atton, France

  ⨯
• Frank Boué,

  Roles Investigation, Methodology

  Affiliation Nancy laboratory for rabies and wildlife, ANSES, Lyssavirus Unit, Malzéville, France

  https://orcid.org/0000-0003-0957-1320

  ⨯
• Nathan Cebron,

  Roles Investigation, Methodology

  Affiliation Ecole nationale vétérinaire de Toulouse, ENVT, INRAE, UMR 1225, IHAP, Université de Toulouse, Toulouse, France

  ⨯
• Blandine Gausserès,

  Roles Investigation, Methodology

  Affiliation Ecole nationale vétérinaire de Toulouse, ENVT, INRAE, UMR 1225, IHAP, Université de Toulouse, Toulouse, France

  ⨯
• Catherine Trumel,

  Roles Investigation, Methodology

  Affiliation Ecole nationale vétérinaire de Toulouse, ENVT, CREFRE, INSERM, Université de Toulouse, Toulouse, France

  https://orcid.org/0000-0001-9717-5808

  ⨯
• Gilles Foucras,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Ecole nationale vétérinaire de Toulouse, ENVT, INRAE, UMR 1225, IHAP, Université de Toulouse, Toulouse, France

  https://orcid.org/0000-0002-0363-0337

  ⨯
• Francisco J. Salguero,

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation National Infection Service, Public Health England (PHE), Porton Down, Salisbury, Wiltshire, United Kingdom

  https://orcid.org/0000-0002-5315-3882

  ⨯
• Elodie Monchatre-Leroy,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Supervision

  Affiliation Nancy laboratory for rabies and wildlife, ANSES, Lyssavirus Unit, Malzéville, France

  https://orcid.org/0000-0002-3231-398X

  ⨯
•  [ ... ],
• Romain Volmer

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: romain.volmer@envt.fr

  Affiliation Ecole nationale vétérinaire de Toulouse, ENVT, INRAE, UMR 1225, IHAP, Université de Toulouse, Toulouse, France

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