Adenovirus-vectored T cell vaccine for hepacivirus shows reduced effectiveness against a CD8 T cell escape variant in rats

• Alex S. Hartlage,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, Ohio, United States of America, Medical Scientist Training Program, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio, United States of America

  https://orcid.org/0000-0002-8414-2959

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• Piyush Dravid,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, Ohio, United States of America

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• Christopher M. Walker,

  Roles Investigation, Methodology, Resources, Writing – review & editing

  Affiliations Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, Ohio, United States of America, Department of Pediatrics, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio, United States of America

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• Amit Kapoor

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: amit.kapoor@nationwidechildrens.org

  Affiliations Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, Ohio, United States of America, Department of Pediatrics, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio, United States of America

  https://orcid.org/0000-0002-8117-7347

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