Treponema denticola dentilisin triggered TLR2/MyD88 activation upregulates a tissue destructive program involving MMPs via Sp1 in human oral cells

• Sean Ganther,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, California, United States of America

  https://orcid.org/0000-0001-7553-155X

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• Allan Radaic,

  Roles Conceptualization, Formal analysis, Methodology

  Affiliation Department of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, California, United States of America

  https://orcid.org/0000-0002-0899-9061

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• Erin Malone,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, California, United States of America

  https://orcid.org/0000-0001-8356-7413

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• Pachiyappan Kamarajan,

  Roles Conceptualization, Data curation, Investigation

  Affiliation Department of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, California, United States of America

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• Nai-Yuan Nicholas Chang,

  Roles Formal analysis, Software

  Affiliation Department of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, California, United States of America

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• Christian Tafolla,

  Roles Data curation

  Affiliation Department of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, California, United States of America

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• Ling Zhan,

  Roles Conceptualization, Investigation, Methodology

  Affiliation Department of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, California, United States of America

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• J. Christopher Fenno,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Department of Biological and Material Sciences & Prosthodontics, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-7073-7855

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• Yvonne L. Kapila

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: Yvonne.Kapila@ucsf.edu

  Affiliation Department of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, California, United States of America

  https://orcid.org/0000-0003-1330-0654

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