Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity

• Fionna A. Surette ,

  Contributed equally to this work with: Fionna A. Surette, Jenna J. Guthmiller

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Immunology Graduate Program, University of Iowa, Iowa City, Iowa, United States of America

  ⨯
• Jenna J. Guthmiller ,

  Contributed equally to this work with: Fionna A. Surette, Jenna J. Guthmiller

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine, Section of Rheumatology, The Knapp Center for Lupus and Immunology Research, The University of Chicago, Chicago, Illinois, United States of America

  https://orcid.org/0000-0001-7566-3536

  ⨯
• Lei Li,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft

  Affiliation Department of Medicine, Section of Rheumatology, The Knapp Center for Lupus and Immunology Research, The University of Chicago, Chicago, Illinois, United States of America

  https://orcid.org/0000-0002-8828-5199

  ⨯
• Alexandria J. Sturtz,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

  https://orcid.org/0000-0001-6548-5086

  ⨯
• Rahul Vijay,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

  ⨯
• Rosemary L. Pope,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Medicine, Section of Rheumatology, The Knapp Center for Lupus and Immunology Research, The University of Chicago, Chicago, Illinois, United States of America

  https://orcid.org/0000-0002-6808-2431

  ⨯
• Brandon L. McClellan,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

  https://orcid.org/0000-0001-8505-3854

  ⨯
• Angela D. Pack,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

  https://orcid.org/0000-0002-7579-2343

  ⨯
• Ryan A. Zander,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States of America

  ⨯
• Peng Shao,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

  https://orcid.org/0000-0002-8453-6480

  ⨯
• Linda Yu-Ling Lan,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Committee on Immunology, The University of Chicago, Chicago, Illinois, United States of America

  ⨯
• Daniel Fernandez-Ruiz,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia

  https://orcid.org/0000-0002-4040-9121

  ⨯
• William R. Heath,

  Roles Methodology, Resources, Writing – review & editing

  Affiliations Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia, ARC Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Parkville, Australia

  https://orcid.org/0000-0001-9670-259X

  ⨯
• Patrick C. Wilson,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Medicine, Section of Rheumatology, The Knapp Center for Lupus and Immunology Research, The University of Chicago, Chicago, Illinois, United States of America

  ⨯
• Noah S. Butler

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: noah-butler@uiowa.edu

  Affiliations Immunology Graduate Program, University of Iowa, Iowa City, Iowa, United States of America, Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America

  https://orcid.org/0000-0002-1429-0796

  ⨯