ASC-dependent inflammasomes contribute to immunopathology and mortality in herpes simplex encephalitis

• Cooper K. Hayes,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America

  https://orcid.org/0000-0003-2419-0286

  ⨯
• Douglas R. Wilcox,

  Roles Conceptualization, Writing – review & editing

  Affiliations Department of Neurology, Brigham and Women’s Hospital, Boston, MA, United States of America, Department of Neurology, Massachusetts General Hospital, Boston, MA, United States of America, Department of Neurology, Harvard Medical School, Boston, MA, United States of America

  ⨯
• Yuchen Yang,

  Roles Formal analysis, Investigation

  Affiliation Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America

  https://orcid.org/0000-0002-0676-5122

  ⨯
• Grace K. Coleman,

  Roles Investigation

  Affiliation Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America

  https://orcid.org/0000-0001-7173-8422

  ⨯
• Melissa A. Brown,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America

  https://orcid.org/0000-0001-7068-088X

  ⨯
• Richard Longnecker

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  * E-mail: r-longnecker@northwestern.edu

  Affiliation Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America

  https://orcid.org/0000-0001-7175-6217

  ⨯