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Open Access
Peer-reviewed
Research Article
Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins
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Kim M. Bouwman ,
Contributed equally to this work with: Kim M. Bouwman, Ilhan Tomris
Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing
Affiliation Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
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Ilhan Tomris ,
Contributed equally to this work with: Kim M. Bouwman, Ilhan Tomris
Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing
Affiliation Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
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Hannah L. Turner,
Roles Data curation, Visualization, Writing – review & editing
Affiliation Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America
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Roosmarijn van der Woude,
Roles Data curation, Writing – review & editing
Affiliation Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
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Tatiana M. Shamorkina,
Roles Data curation, Writing – review & editing
Affiliations Biomolecular Mass Spectrometry and Proteomics, Department of Chemistry, Faculty of Science, Utrecht University, Utrecht, The Netherlands, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands
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Gerlof P. Bosman,
Roles Data curation, Writing – review & editing
Affiliation Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
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Barry Rockx,
Roles Resources, Writing – review & editing
Affiliation Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands
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Sander Herfst,
Roles Funding acquisition, Resources, Writing – review & editing
Affiliation Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands
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Joost Snijder,
Roles Funding acquisition, Software, Writing – review & editing
Affiliations Biomolecular Mass Spectrometry and Proteomics, Department of Chemistry, Faculty of Science, Utrecht University, Utrecht, The Netherlands, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands
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Bart L. Haagmans,
Roles Resources, Writing – review & editing
Affiliation Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands
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Andrew B. Ward,
Roles Funding acquisition, Supervision, Writing – review & editing
Affiliation Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America
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Geert-Jan Boons,
Roles Funding acquisition, Supervision, Writing – review & editing
Affiliations Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands, Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, United States of America, Department of Chemistry, University of Georgia, Athens, Georgia, United States of America
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Robert P. de Vries
Roles Conceptualization, Funding acquisition, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: r.vries@uu.nl
Affiliation Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
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Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins
- Kim M. Bouwman,
- Ilhan Tomris,
- Hannah L. Turner,
- Roosmarijn van der Woude,
- Tatiana M. Shamorkina,
- Gerlof P. Bosman,
- Barry Rockx,
- Sander Herfst,
- Joost Snijder,
- Bart L. Haagmans
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- Published: February 8, 2021
- https://doi.org/10.1371/journal.ppat.1009282