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Open Access
Peer-reviewed
Research Article
Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy
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Fredrik Barrenäs,
Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden
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Scott G. Hansen,
Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization
Affiliation Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America
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Lynn Law,
Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization
Affiliation Center for Innate Immunity and Immune Disease, Department of Immunology, University of Washington, Seattle, Washington, United States of America
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Connor Driscoll,
Roles Data curation, Formal analysis, Visualization
Affiliation Center for Innate Immunity and Immune Disease, Department of Immunology, University of Washington, Seattle, Washington, United States of America
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Richard R. Green,
Roles Data curation, Formal analysis, Investigation, Visualization
Affiliation Center for Innate Immunity and Immune Disease, Department of Immunology, University of Washington, Seattle, Washington, United States of America
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Elise Smith,
Roles Data curation, Formal analysis, Methodology, Validation
Affiliation Center for Innate Immunity and Immune Disease, Department of Immunology, University of Washington, Seattle, Washington, United States of America
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Jean Chang,
Roles Data curation, Formal analysis
Affiliation Center for Innate Immunity and Immune Disease, Department of Immunology, University of Washington, Seattle, Washington, United States of America
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Inah Golez,
Roles Data curation, Formal analysis
Affiliation Center for Innate Immunity and Immune Disease, Department of Immunology, University of Washington, Seattle, Washington, United States of America
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Taryn Urion,
Roles Data curation, Formal analysis
Affiliation Center for Innate Immunity and Immune Disease, Department of Immunology, University of Washington, Seattle, Washington, United States of America
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Xinxia Peng,
Roles Data curation, Formal analysis, Methodology, Software, Validation, Visualization
Affiliation Department of Molecular Biomedical Sciences and Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, United States of America
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Leanne Whitmore,
Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – review & editing
Affiliation Center for Innate Immunity and Immune Disease, Department of Immunology, University of Washington, Seattle, Washington, United States of America
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Daniel Newhouse,
Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – review & editing
Affiliation Center for Innate Immunity and Immune Disease, Department of Immunology, University of Washington, Seattle, Washington, United States of America
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Colette M. Hughes,
Roles Data curation, Investigation, Supervision
Affiliation Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America
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David Morrow,
Roles Investigation
Affiliation Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America
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Kurt T. Randall,
Roles Investigation
Affiliation Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America
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Andrea N. Selseth,
Roles Investigation
Affiliation Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America
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Julia C. Ford,
Roles Investigation
Affiliation Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America
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Roxanne M. Gilbride,
Roles Investigation, Supervision
Affiliation Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America
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Bryan E. Randall,
Roles Investigation
Affiliation Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America
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Emily Ainslie,
Roles Investigation
Affiliation Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America
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Kelli Oswald,
Roles Investigation
Affiliation AIDS and Cancer Virus Program, SAIC Frederick, Inc., Frederick National Laboratory, Leidos Biomedical Research, Inc., Frederick, Maryland, United States of America
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Rebecca Shoemaker,
Roles Investigation
Affiliation AIDS and Cancer Virus Program, SAIC Frederick, Inc., Frederick National Laboratory, Leidos Biomedical Research, Inc., Frederick, Maryland, United States of America
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Randy Fast,
Roles Investigation
Affiliation AIDS and Cancer Virus Program, SAIC Frederick, Inc., Frederick National Laboratory, Leidos Biomedical Research, Inc., Frederick, Maryland, United States of America
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William J. Bosche,
Roles Investigation
Affiliation AIDS and Cancer Virus Program, SAIC Frederick, Inc., Frederick National Laboratory, Leidos Biomedical Research, Inc., Frederick, Maryland, United States of America
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Michael K. Axthelm,
Roles Investigation, Methodology, Resources, Supervision
Affiliation Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America
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Yoshinori Fukazawa,
Roles Data curation, Investigation, Methodology
Affiliation Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America
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George N. Pavlakis,
Roles Methodology, Resources
Affiliation Human Retrovirus Section, Vaccine Branch, National Cancer Institute at Frederick, Frederick, Maryland, United States of America
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Barbara K. Felber,
Roles Methodology, Resources
Affiliation Human Retrovirus Pathogenesis Section, Vaccine Branch, National Cancer Institute at Frederick, Frederick, Maryland, United States of America
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Slim Fourati,
Roles Investigation, Validation, Visualization
Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America
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Rafick-Pierre Sekaly,
Roles Conceptualization, Supervision
Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America
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Jeffrey D. Lifson,
Roles Conceptualization, Supervision, Writing – review & editing
Affiliation AIDS and Cancer Virus Program, SAIC Frederick, Inc., Frederick National Laboratory, Leidos Biomedical Research, Inc., Frederick, Maryland, United States of America
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Jan Komorowski,
Roles Conceptualization, Resources
Affiliation Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden
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Ewelina Kosmider,
Roles Formal analysis, Validation, Visualization
Affiliation Statistical Center for HIV/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Danica Shao,
Roles Formal analysis, Validation, Visualization
Affiliation Statistical Center for HIV/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Wenjun Song,
Roles Formal analysis, Validation, Visualization
Affiliation Statistical Center for HIV/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Paul T. Edlefsen,
Roles Conceptualization, Formal analysis, Investigation, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Statistical Center for HIV/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Louis J. Picker ,
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: pickerl@ohsu.edu (LP); mgale@uw.edu (MG)
Affiliation Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, United States of America
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Michael Gale Jr
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: pickerl@ohsu.edu (LP); mgale@uw.edu (MG)
Affiliation Center for Innate Immunity and Immune Disease, Department of Immunology, University of Washington, Seattle, Washington, United States of America
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Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy
- Fredrik Barrenäs,
- Scott G. Hansen,
- Lynn Law,
- Connor Driscoll,
- Richard R. Green,
- Elise Smith,
- Jean Chang,
- Inah Golez,
- Taryn Urion,
- Xinxia Peng
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- Published: July 6, 2021
- https://doi.org/10.1371/journal.ppat.1009278