EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape

Nathan Ungerleider; Whitney Bullard; Mehmet Kara; Xia Wang; Claire Roberts; Rolf Renne; Scott Tibbetts; Erik K. Flemington

doi:10.1371/journal.ppat.1009217

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Open Access

Peer-reviewed

Research Article

EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape

Nathan Ungerleider,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Pathology, Tulane University School of Medicine, Tulane Cancer Center, New Orleans, Louisiana, United States of America
⨯
Whitney Bullard,

Roles Investigation

Affiliation Department of Molecular Genetics and Microbiology, UF Health Cancer Center, University of Florida, Gainesville, Florida, United States of America

https://orcid.org/0000-0002-2228-859X

⨯
Mehmet Kara,

Roles Investigation

Affiliation Department of Molecular Genetics and Microbiology, UF Health Cancer Center, University of Florida, Gainesville, Florida, United States of America

https://orcid.org/0000-0002-9646-4584

⨯
Xia Wang,

Roles Investigation

Affiliation Department of Pathology, Tulane University School of Medicine, Tulane Cancer Center, New Orleans, Louisiana, United States of America
⨯
Claire Roberts,

Roles Investigation

Affiliation Department of Pathology, Tulane University School of Medicine, Tulane Cancer Center, New Orleans, Louisiana, United States of America

https://orcid.org/0000-0002-0126-1531

⨯
Rolf Renne,

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Department of Molecular Genetics and Microbiology, UF Health Cancer Center, University of Florida, Gainesville, Florida, United States of America

https://orcid.org/0000-0001-7391-8806

⨯
Scott Tibbetts ,

Roles Conceptualization, Writing – review & editing

* E-mail: stibbe@ufl.edu (ST); erik@tulane.edu (EKF)

Affiliation Department of Molecular Genetics and Microbiology, UF Health Cancer Center, University of Florida, Gainesville, Florida, United States of America

https://orcid.org/0000-0001-8889-1642

⨯
Erik K. Flemington

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Writing – original draft, Writing – review & editing

* E-mail: stibbe@ufl.edu (ST); erik@tulane.edu (EKF)

Affiliation Department of Pathology, Tulane University School of Medicine, Tulane Cancer Center, New Orleans, Louisiana, United States of America

https://orcid.org/0000-0003-0513-5281

⨯

EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape

Nathan Ungerleider,
Whitney Bullard,
Mehmet Kara,
Xia Wang,
Claire Roberts,
Rolf Renne,
Scott Tibbetts,
Erik K. Flemington

Published: May 6, 2021
https://doi.org/10.1371/journal.ppat.1009217

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MicroRNAs
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Cancers and neoplasms
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RNA sequencing
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Transcriptome analysis
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Malignant tumors
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Immune response
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T cells
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Viral gene expression
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