Signal peptide of HIV-1 envelope modulates glycosylation impacting exposure of V1V2 and other epitopes

• Chitra Upadhyay ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Chitra.Upadhyay@mssm.edu

  Affiliations Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, James J. Peters Veterans Affairs Medical Center, Research Service, Bronx, New York, United States of America

  https://orcid.org/0000-0002-4524-1532

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• Roya Feyznezhad,

  Roles Investigation

  Affiliation Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

  https://orcid.org/0000-0002-0895-6782

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• Liwei Cao,

  Roles Investigation

  Affiliation Johns Hopkins University, Baltimore, Maryland, United States of America

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• Kun-Wei Chan,

  Roles Investigation

  Affiliation Department of Biochemistry and Molecular Pharmacology New York University School of Medicine, New York, New York, United States of America

  https://orcid.org/0000-0001-5384-6198

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• Kevin Liu,

  Roles Investigation

  Affiliation Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

  https://orcid.org/0000-0002-0977-2694

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• Weiming Yang,

  Roles Investigation

  Affiliation Johns Hopkins University, Baltimore, Maryland, United States of America

  https://orcid.org/0000-0002-5023-2155

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• Hui Zhang,

  Roles Resources

  Affiliation Johns Hopkins University, Baltimore, Maryland, United States of America

  https://orcid.org/0000-0001-8726-7098

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• Jason Yolitz,

  Roles Investigation

  Affiliation Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0002-2453-6171

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• James Arthos,

  Roles Resources

  Affiliation Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Arthur Nadas,

  Roles Formal analysis

  Affiliation Institute of Environmental Medicine, New York University School of Medicine, New York, New York, United States of America

  https://orcid.org/0000-0002-6893-6759

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• Xiang-Peng Kong,

  Roles Resources

  Affiliation Department of Biochemistry and Molecular Pharmacology New York University School of Medicine, New York, New York, United States of America

  https://orcid.org/0000-0001-5773-2681

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• Susan Zolla-Pazner,

  Roles Resources

  Affiliation Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

  https://orcid.org/0000-0002-0750-2666

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• Catarina E. Hioe

  Roles Funding acquisition, Writing – review & editing

  Affiliations Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, James J. Peters Veterans Affairs Medical Center, Research Service, Bronx, New York, United States of America

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