Targeting bioenergetics is key to counteracting the drug-tolerant state of biofilm-grown bacteria

• Monique Donnert,

  Roles Conceptualization, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Institute of Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany

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• Sarah Elsheikh,

  Roles Investigation, Methodology

  Affiliation Institute of Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany

  https://orcid.org/0000-0001-7839-5960

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• Alejandro Arce-Rodriguez,

  Roles Investigation, Methodology

  Affiliation Department of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig, Germany

  https://orcid.org/0000-0002-2486-401X

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• Vinay Pawar,

  Roles Investigation

  Affiliations Institute of Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany, Department of Molecular Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany, Institute of Immunology, Hannover Medical School, Hannover, Germany

  https://orcid.org/0000-0003-0055-1091

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• Peter Braubach,

  Roles Investigation

  Affiliations Institute of Pathology, Hannover Medical School, Hannover, Germany, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (Deutsches Zentrum für Lungenforschung [DZL]), Hannover, Germany

  https://orcid.org/0000-0003-3673-7779

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• Danny Jonigk,

  Roles Resources

  Affiliations Institute of Pathology, Hannover Medical School, Hannover, Germany, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (Deutsches Zentrum für Lungenforschung [DZL]), Hannover, Germany

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• Axel Haverich,

  Roles Resources

  Affiliations Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (Deutsches Zentrum für Lungenforschung [DZL]), Hannover, Germany, Department of Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany

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• Siegfried Weiss,

  Roles Methodology, Resources, Writing – review & editing

  Affiliations Institute of Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany, Department of Molecular Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany, Institute of Immunology, Hannover Medical School, Hannover, Germany

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• Mathias Müsken,

  Roles Conceptualization, Supervision

  Affiliations Institute of Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany, Department of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig, Germany, Central Facility for Microscopy, Helmholtz Centre for Infection Research, Braunschweig, Germany

  https://orcid.org/0000-0002-5624-1378

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• Susanne Häussler

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Susanne.haeussler@helmholtz-hzi.de

  Affiliations Institute of Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany, Department of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig, Germany, Department of Clinical Microbiology, Copenhagen University Hospital–Rigshospitalet, Copenhagen, Denmark, Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany

  https://orcid.org/0000-0001-6141-9102

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