Impact of vaginal microbiome communities on HIV antiretroviral-based pre-exposure prophylaxis (PrEP) drug metabolism

• Ryan K. Cheu,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft

  Affiliations Department of Pharmaceutics, University of Washington, Seattle, Washington, United States of America, Washington National Primate Research Center, University of Washington, Seattle, Washington, United States of America, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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• Andrew T. Gustin,

  Roles Formal analysis, Investigation

  Affiliations Department of Pharmaceutics, University of Washington, Seattle, Washington, United States of America, Washington National Primate Research Center, University of Washington, Seattle, Washington, United States of America, Division of Surgical Outcomes and Precision Medicine Research, Department of Surgery, University of Minnesota, Minneapolis, Minnesota, United States of America

  https://orcid.org/0000-0002-8760-8320

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• Christina Lee,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0002-9393-2178

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• Luca Schifanella,

  Roles Supervision, Validation, Writing – review & editing

  Affiliation Division of Surgical Outcomes and Precision Medicine Research, Department of Surgery, University of Minnesota, Minneapolis, Minnesota, United States of America

  https://orcid.org/0000-0002-6123-536X

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• Charlene J. Miller,

  Roles Investigation

  Affiliations Department of Pharmaceutics, University of Washington, Seattle, Washington, United States of America, Washington National Primate Research Center, University of Washington, Seattle, Washington, United States of America, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, Florida, United States of America

  https://orcid.org/0000-0002-0090-6465

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• Avie Ha,

  Roles Investigation

  Affiliations Department of Pharmaceutics, University of Washington, Seattle, Washington, United States of America, Washington National Primate Research Center, University of Washington, Seattle, Washington, United States of America

  https://orcid.org/0000-0003-2769-3567

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• Casey Kim,

  Roles Investigation

  Affiliations Department of Pharmaceutics, University of Washington, Seattle, Washington, United States of America, Washington National Primate Research Center, University of Washington, Seattle, Washington, United States of America

  https://orcid.org/0000-0002-7109-6076

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• Violeta J. Rodriguez,

  Roles Resources

  Affiliations Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Department of Psychology, University of Georgia, Athens, Georgia, United States of America

  https://orcid.org/0000-0001-8543-2061

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• Margaret Fischl,

  Roles Resources

  Affiliation Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America

  https://orcid.org/0000-0001-9241-5390

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• Adam D. Burgener,

  Roles Methodology

  Affiliations Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada, Center for Global Health and Disease, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Kelly B. Arnold,

  Roles Methodology, Supervision

  Affiliation Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America

  https://orcid.org/0000-0003-4756-7461

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• Maria L. Alcaide,

  Roles Resources

  Affiliation Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America

  https://orcid.org/0000-0003-4648-0145

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• Nichole R. Klatt

  Roles Conceptualization, Formal analysis, Resources, Supervision, Writing – original draft

  * E-mail: klat0037@umn.edu

  Affiliations Department of Pharmaceutics, University of Washington, Seattle, Washington, United States of America, Washington National Primate Research Center, University of Washington, Seattle, Washington, United States of America, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Division of Surgical Outcomes and Precision Medicine Research, Department of Surgery, University of Minnesota, Minneapolis, Minnesota, United States of America

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