A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response

• Rujapak Sutiwisesak,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – original draft

  Affiliations Immunology and Microbiology Program, Graduate School of Biomedical Science, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

  https://orcid.org/0000-0001-9685-3662

  ⨯
• Nathan D. Hicks,

  Roles Data curation, Formal analysis, Investigation, Validation, Visualization

  Affiliation Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-6631-8383

  ⨯
• Shayla Boyce,

  Roles Data curation, Formal analysis, Investigation, Validation

  Affiliation Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

  ⨯
• Kenan C. Murphy,

  Roles Methodology

  Affiliations Immunology and Microbiology Program, Graduate School of Biomedical Science, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

  https://orcid.org/0000-0002-3677-2876

  ⨯
• Kadamba Papavinasasundaram,

  Roles Methodology

  Affiliation Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

  ⨯
• Stephen M. Carpenter,

  Roles Data curation, Formal analysis, Investigation, Validation

  Affiliation Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

  https://orcid.org/0000-0001-9879-327X

  ⨯
• Julie Boucau,

  Roles Data curation, Formal analysis, Investigation, Validation

  Affiliation Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America

  https://orcid.org/0000-0001-6731-7238

  ⨯
• Neelambari Joshi,

  Roles Data curation, Formal analysis, Investigation, Validation

  Affiliation Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America

  ⨯
• Sylvie Le Gall,

  Roles Visualization

  Affiliation Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America

  ⨯
• Sarah M. Fortune,

  Roles Funding acquisition, Project administration, Supervision

  Affiliation Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America

  ⨯
• Christopher M. Sassetti,

  Roles Funding acquisition, Project administration, Supervision

  Affiliations Immunology and Microbiology Program, Graduate School of Biomedical Science, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

  ⨯
• Samuel M. Behar

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft

  * E-mail: samuel.behar@umassmed.edu

  Affiliations Immunology and Microbiology Program, Graduate School of Biomedical Science, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

  https://orcid.org/0000-0002-3374-6699

  ⨯