Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis

• Alexander Lercher ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: lercher.alexander@gmail.com (AL); abergthaler@cemm.oeaw.ac.at (AB)

  Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse, Vienna, Austria

  https://orcid.org/0000-0003-3478-5304

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• Alexandra M. Popa,

  Roles Data curation, Formal analysis, Methodology

  Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse, Vienna, Austria

  https://orcid.org/0000-0001-7156-272X

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• Csilla Viczenczova,

  Roles Methodology

  Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse, Vienna, Austria

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• Lindsay Kosack,

  Roles Methodology

  Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse, Vienna, Austria

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• Kristaps Klavins,

  Roles Methodology

  Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse, Vienna, Austria

  https://orcid.org/0000-0001-9577-9990

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• Benedikt Agerer,

  Roles Methodology

  Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse, Vienna, Austria

  https://orcid.org/0000-0002-0044-8396

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• Christiane A. Opitz,

  Roles Resources

  Affiliations DKTK Brain Cancer Metabolism Group, German Cancer Research Center (DKFZ), Heidelberg, Germany, Neurology Clinic and National Center for Tumor Diseases, University Hospital of Heidelberg, Heidelberg, Germany

  https://orcid.org/0000-0001-5575-9821

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• Tobias V. Lanz,

  Roles Resources

  Affiliations Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States of America, Department of Neurology, University of Heidelberg, Medical Faculty Mannheim, Mannheim, Germany

  https://orcid.org/0000-0001-7106-8801

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• Michael Platten,

  Roles Resources

  Affiliations Department of Neurology, University of Heidelberg, Medical Faculty Mannheim, Mannheim, Germany, DKTK Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany

  https://orcid.org/0000-0002-4746-887X

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• Andreas Bergthaler

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: lercher.alexander@gmail.com (AL); abergthaler@cemm.oeaw.ac.at (AB)

  Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse, Vienna, Austria

  https://orcid.org/0000-0003-0597-1976

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