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Open Access
Peer-reviewed
Research Article
YebC regulates variable surface antigen VlsE expression and is required for host immune evasion in Borrelia burgdorferi
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Yan Zhang ,
Contributed equally to this work with: Yan Zhang, Tong Chen, Sajith Raghunandanan
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft
Affiliations Wenzhou Key Laboratory of Sanitary Microbiology, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China, Optometry and Eye Hospital and School of Ophthalmology, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou, China, Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Tong Chen ,
Contributed equally to this work with: Yan Zhang, Tong Chen, Sajith Raghunandanan
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft
Affiliations Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Pediatrics, Division of Medical Genetics, Duke University, Durham, North Carolina, United States of America
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Sajith Raghunandanan ,
Contributed equally to this work with: Yan Zhang, Tong Chen, Sajith Raghunandanan
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Xuwu Xiang,
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliation Department of Anesthesiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
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Jing Yang,
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliations Wenzhou Key Laboratory of Sanitary Microbiology, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China, Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Qiang Liu,
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliations Wenzhou Key Laboratory of Sanitary Microbiology, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China, Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Diane G. Edmondson,
Roles Formal analysis, Writing – review & editing
Affiliation Department of Pathology and Laboratory Medicine, UTHealth Medical School, Houston, Texas, United States of America
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Steven J. Norris,
Roles Formal analysis, Writing – review & editing
Affiliation Department of Pathology and Laboratory Medicine, UTHealth Medical School, Houston, Texas, United States of America
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X. Frank Yang ,
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: xfyang@iu.edu (XFY); lyl@wmu.edu.cn (YL)
Affiliation Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Yongliang Lou
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft
* E-mail: xfyang@iu.edu (XFY); lyl@wmu.edu.cn (YL)
Affiliation Wenzhou Key Laboratory of Sanitary Microbiology, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China
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YebC regulates variable surface antigen VlsE expression and is required for host immune evasion in Borrelia burgdorferi
- Yan Zhang,
- Tong Chen,
- Sajith Raghunandanan,
- Xuwu Xiang,
- Jing Yang,
- Qiang Liu,
- Diane G. Edmondson,
- Steven J. Norris,
- X. Frank Yang,
- Yongliang Lou
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- Published: October 13, 2020
- https://doi.org/10.1371/journal.ppat.1008953