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Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1α activation
- Melanie Genoula,
- José Luis Marín Franco,
- Mariano Maio,
- Belén Dolotowicz,
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Malena Ferreyra,
Roles Investigation
Affiliation Instituto de Medicina Experimental (IMEX)-CONICET, Academia Nacional de Medicina, Buenos Aires, Argentina
⨯ - M. Ayelén Milillo,
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Rémi Mascarau,
Roles Investigation, Visualization
Affiliation Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, Toulouse, France
⨯ - Eduardo José Moraña,
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Domingo Palmero,
Roles Resources, Writing – review & editing
Affiliation Instituto Prof. Dr. Raúl Vaccarezza, Hospital de Infecciosas Dr. F.J. Muñiz, Buenos Aires, Argentina
⨯ - Mario Matteo,
- Federico Fuentes,
- Beatriz López,
- Paula Barrionuevo,
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Olivier Neyrolles,
Roles Funding acquisition, Resources, Writing – review & editing
Affiliations International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina—Toulouse, France, Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, Toulouse, France
⨯ - Céline Cougoule,
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Geanncarlo Lugo-Villarino,
Roles Investigation, Resources, Writing – review & editing
Affiliations International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina—Toulouse, France, Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, Toulouse, France
⨯ - Christel Vérollet,
- María del Carmen Sasiain,
- [ ... ],
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Luciana Balboa
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: luciana_balboa@hotmail.com
Affiliations Instituto de Medicina Experimental (IMEX)-CONICET, Academia Nacional de Medicina, Buenos Aires, Argentina, International Associated Laboratory (LIA) CNRS IM-TB/HIV (1167), Buenos Aires, Argentina—Toulouse, France
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http://orcid.org/0000-0002-3111-6546
Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1α activation
- Melanie Genoula,
- José Luis Marín Franco,
- Mariano Maio,
- Belén Dolotowicz,
- Malena Ferreyra,
- M. Ayelén Milillo,
- Rémi Mascarau,
- Eduardo José Moraña,
- Domingo Palmero,
- Mario Matteo
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- Published: October 1, 2020
- https://doi.org/10.1371/journal.ppat.1008929