Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis

• Amit Luthra ,

  Contributed equally to this work with: Amit Luthra, Jairo M. Montezuma-Rusca

  Roles Conceptualization, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine, UConn Health, Farmington, United States of America

  ⨯
• Jairo M. Montezuma-Rusca ,

  Contributed equally to this work with: Amit Luthra, Jairo M. Montezuma-Rusca

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Medicine, UConn Health, Farmington, United States of America, Division of Infectious Diseases, UConn Health, Farmington, United States of America, Department of Pediatrics, UConn Health, Farmington, United States of America

  http://orcid.org/0000-0002-8391-1242

  ⨯
• Carson J. La Vake,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Pediatrics, UConn Health, Farmington, United States of America

  http://orcid.org/0000-0001-8894-7298

  ⨯
• Morgan LeDoyt,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Medicine, UConn Health, Farmington, United States of America

  http://orcid.org/0000-0001-7880-6854

  ⨯
• Kristina N. Delgado,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Medicine, UConn Health, Farmington, United States of America

  http://orcid.org/0000-0003-3041-5170

  ⨯
• Timothy C. Davenport,

  Roles Methodology, Writing – review & editing

  Current address: Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53715, United States of America

  Affiliation Department of Medicine, UConn Health, Farmington, United States of America

  ⨯
• Mary Fiel-Gan,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Pathology, Hartford Hospital, Hartford, United States of America

  ⨯
• Melissa J. Caimano,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Writing – review & editing

  Affiliations Department of Medicine, UConn Health, Farmington, United States of America, Department of Pediatrics, UConn Health, Farmington, United States of America, Department of Molecular Biology and Biophysics, UConn Health, Farmington, United States of America

  http://orcid.org/0000-0003-1170-4102

  ⨯
• Justin D. Radolf,

  Roles Conceptualization, Formal analysis, Funding acquisition, Writing – original draft, Writing – review & editing

  Affiliations Department of Medicine, UConn Health, Farmington, United States of America, Department of Pediatrics, UConn Health, Farmington, United States of America, Department of Molecular Biology and Biophysics, UConn Health, Farmington, United States of America, Department of Genetics and Genome Sciences, UConn Health, Farmington, United States of America, Department of Immunology, UConn Health, Farmington, United States of America

  ⨯
• Kelly L. Hawley

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: hawley@uchc.edu

  Affiliations Department of Pediatrics, UConn Health, Farmington, United States of America, Division of Infectious Diseases and Immunology, Connecticut Children’s, Hartford, United States of America

  http://orcid.org/0000-0001-8587-1662

  ⨯