NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis

Bridget Kastelberg; Nuria Tubau-Juni; Tariq Ayubi; Austin Leung; Andrew Leber; Raquel Hontecillas; Josep Bassaganya-Riera; Shiv D. Kale

doi:10.1371/journal.ppat.1008854

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Open Access

Peer-reviewed

Research Article

NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis

Bridget Kastelberg ,

Contributed equally to this work with: Bridget Kastelberg, Nuria Tubau-Juni

Roles Data curation, Formal analysis, Investigation, Methodology, Validation

Affiliation Nutritional Immunology and Molecular Medicine Institute, Blacksburg, Virginia, United States of America

http://orcid.org/0000-0002-6039-5898

⨯
Nuria Tubau-Juni ,

Contributed equally to this work with: Bridget Kastelberg, Nuria Tubau-Juni

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Nutritional Immunology and Molecular Medicine Institute, Blacksburg, Virginia, United States of America

http://orcid.org/0000-0002-5787-8055

⨯
Tariq Ayubi,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Nutritional Immunology and Molecular Medicine Institute, Blacksburg, Virginia, United States of America

http://orcid.org/0000-0001-7233-9749

⨯
Austin Leung,

Roles Formal analysis, Investigation

Affiliation Nutritional Immunology and Molecular Medicine Institute, Blacksburg, Virginia, United States of America

http://orcid.org/0000-0002-8394-4212

⨯
Andrew Leber,

Roles Formal analysis, Investigation, Methodology, Supervision

Affiliation Nutritional Immunology and Molecular Medicine Institute, Blacksburg, Virginia, United States of America
⨯
Raquel Hontecillas,

Roles Formal analysis, Supervision, Writing – review & editing

Affiliation Nutritional Immunology and Molecular Medicine Institute, Blacksburg, Virginia, United States of America
⨯
Josep Bassaganya-Riera,

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

Affiliation Nutritional Immunology and Molecular Medicine Institute, Blacksburg, Virginia, United States of America
⨯
Shiv D. Kale

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: shivdkale@gmail.com

Affiliation Nutritional Immunology and Molecular Medicine Institute, Blacksburg, Virginia, United States of America

http://orcid.org/0000-0002-0645-1799

⨯

NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis

Bridget Kastelberg,
Nuria Tubau-Juni,
Tariq Ayubi,
Austin Leung,
Andrew Leber,
Raquel Hontecillas,
Josep Bassaganya-Riera,
Shiv D. Kale

Published: September 21, 2020
https://doi.org/10.1371/journal.ppat.1008854

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Neutrophils
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Aspergillus fumigatus
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Immune receptor signaling
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Immune response
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