Infection with multiple HIV-1 founder variants is associated with lower viral replicative capacity, faster CD4⁺ T cell decline and increased immune activation during acute infection

• Gladys N. Macharia,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Medicine, Imperial College London, London, United Kingdom, IAVI Human Immunology Laboratory, London, United Kingdom

  http://orcid.org/0000-0002-5605-5604

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• Ling Yue,

  Roles Methodology

  Affiliation Emory Vaccine Centre, Yerkes National Primate Research Centre, Emory University, Atlanta, GA, United States of America

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• Ecco Staller,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliations Department of Medicine, Imperial College London, London, United Kingdom, IAVI Human Immunology Laboratory, London, United Kingdom

  http://orcid.org/0000-0002-8443-5559

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• Dario Dilernia,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Emory Vaccine Centre, Yerkes National Primate Research Centre, Emory University, Atlanta, GA, United States of America

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• Daniel Wilkins,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Emory Vaccine Centre, Yerkes National Primate Research Centre, Emory University, Atlanta, GA, United States of America

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• Heeyah Song,

  Roles Investigation, Methodology

  Affiliation Emory Vaccine Centre, Yerkes National Primate Research Centre, Emory University, Atlanta, GA, United States of America

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• Edward McGowan,

  Roles Supervision

  Affiliations Department of Medicine, Imperial College London, London, United Kingdom, IAVI Human Immunology Laboratory, London, United Kingdom

  http://orcid.org/0000-0001-6529-1978

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• Deborah King,

  Roles Supervision, Writing – review & editing

  Affiliations Department of Medicine, Imperial College London, London, United Kingdom, IAVI Human Immunology Laboratory, London, United Kingdom

  http://orcid.org/0000-0003-3199-5728

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• Pat Fast,

  Roles Funding acquisition

  Affiliation IAVI, New York, NY, United States of America

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• Nesrina Imami,

  Roles Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Department of Medicine, Imperial College London, London, United Kingdom

  http://orcid.org/0000-0001-9673-2895

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• Matthew A. Price,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliations IAVI, New York, NY, United States of America, Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, United States of America

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• Eduard J. Sanders,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Writing – review & editing

  Affiliations Kenya Medical Research Institute-Wellcome Trust, Kilifi, Kenya, Nuffield Department of Clinical Medicine, Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Headington, United Kingdom

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• Eric Hunter,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Emory Vaccine Centre, Yerkes National Primate Research Centre, Emory University, Atlanta, GA, United States of America, Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, United States of America

  http://orcid.org/0000-0002-4273-8631

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• Jill Gilmour

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: J.Gilmour@imperial.ac.uk

  Affiliations Department of Medicine, Imperial College London, London, United Kingdom, IAVI Human Immunology Laboratory, London, United Kingdom

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