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Open Access
Peer-reviewed
Research Article
The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing
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Einat Seidel ,
Contributed equally to this work with: Einat Seidel, Liat Dassa, Vu Thuy Khanh Le-Trilling, Ofer Mandelboim
Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliation The Lautenberg Center for General and Tumor Immunology, The Faculty of Medicine, The Hebrew University Medical School, IMRIC, Jerusalem, Israel
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Liat Dassa ,
Contributed equally to this work with: Einat Seidel, Liat Dassa, Vu Thuy Khanh Le-Trilling, Ofer Mandelboim
Roles Conceptualization, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliation The Lautenberg Center for General and Tumor Immunology, The Faculty of Medicine, The Hebrew University Medical School, IMRIC, Jerusalem, Israel
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Corinna Schuler,
Roles Investigation, Visualization
Affiliation Institute for Virology of the University Hospital Essen, University Duisburg-Essen, Essen, Germany
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Esther Oiknine-Djian,
Roles Methodology, Resources
Affiliations Clinical Virology Unit, Hadassah Hebrew University Medical Center, Jerusalem, Israel , Department of Biochemistry, IMRIC, Jerusalem, Israel , The Chanock Center for Virology, IMRIC, Jerusalem, Israel
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Dana G. Wolf,
Roles Conceptualization, Methodology, Resources
Affiliations Clinical Virology Unit, Hadassah Hebrew University Medical Center, Jerusalem, Israel , Department of Biochemistry, IMRIC, Jerusalem, Israel , The Chanock Center for Virology, IMRIC, Jerusalem, Israel
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Vu Thuy Khanh Le-Trilling ,
Contributed equally to this work with: Einat Seidel, Liat Dassa, Vu Thuy Khanh Le-Trilling, Ofer Mandelboim
Roles Conceptualization, Investigation, Methodology, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: Khanh.Le@uk-essen.de (VTKL-T); oferm@ekmd.huji.ac.il (OM)
Affiliation Institute for Virology of the University Hospital Essen, University Duisburg-Essen, Essen, Germany
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Ofer Mandelboim
Contributed equally to this work with: Einat Seidel, Liat Dassa, Vu Thuy Khanh Le-Trilling, Ofer Mandelboim
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: Khanh.Le@uk-essen.de (VTKL-T); oferm@ekmd.huji.ac.il (OM)
Affiliation The Lautenberg Center for General and Tumor Immunology, The Faculty of Medicine, The Hebrew University Medical School, IMRIC, Jerusalem, Israel
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The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing
- Einat Seidel,
- Liat Dassa,
- Corinna Schuler,
- Esther Oiknine-Djian,
- Dana G. Wolf,
- Vu Thuy Khanh Le-Trilling,
- Ofer Mandelboim
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- Published: May 3, 2021
- https://doi.org/10.1371/journal.ppat.1008807