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Open Access
Peer-reviewed
Research Article
The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing
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Einat Seidel ,
Contributed equally to this work with: Einat Seidel, Liat Dassa, Vu Thuy Khanh Le-Trilling, Ofer Mandelboim
Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliation The Lautenberg Center for General and Tumor Immunology, The Faculty of Medicine, The Hebrew University Medical School, IMRIC, Jerusalem, Israel
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Liat Dassa ,
Contributed equally to this work with: Einat Seidel, Liat Dassa, Vu Thuy Khanh Le-Trilling, Ofer Mandelboim
Roles Conceptualization, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliation The Lautenberg Center for General and Tumor Immunology, The Faculty of Medicine, The Hebrew University Medical School, IMRIC, Jerusalem, Israel
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Corinna Schuler,
Roles Investigation, Visualization
Affiliation Institute for Virology of the University Hospital Essen, University Duisburg-Essen, Essen, Germany
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Esther Oiknine-Djian,
Roles Methodology, Resources
Affiliations Clinical Virology Unit, Hadassah Hebrew University Medical Center, Jerusalem, Israel, Department of Biochemistry, IMRIC, Jerusalem, Israel, The Chanock Center for Virology, IMRIC, Jerusalem, Israel
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Dana G. Wolf,
Roles Conceptualization, Methodology, Resources
Affiliations Clinical Virology Unit, Hadassah Hebrew University Medical Center, Jerusalem, Israel, Department of Biochemistry, IMRIC, Jerusalem, Israel, The Chanock Center for Virology, IMRIC, Jerusalem, Israel
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Vu Thuy Khanh Le-Trilling ,
Contributed equally to this work with: Einat Seidel, Liat Dassa, Vu Thuy Khanh Le-Trilling, Ofer Mandelboim
Roles Conceptualization, Investigation, Methodology, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: Khanh.Le@uk-essen.de (VTKL-T); oferm@ekmd.huji.ac.il (OM)
Affiliation Institute for Virology of the University Hospital Essen, University Duisburg-Essen, Essen, Germany
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Ofer Mandelboim
Contributed equally to this work with: Einat Seidel, Liat Dassa, Vu Thuy Khanh Le-Trilling, Ofer Mandelboim
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: Khanh.Le@uk-essen.de (VTKL-T); oferm@ekmd.huji.ac.il (OM)
Affiliation The Lautenberg Center for General and Tumor Immunology, The Faculty of Medicine, The Hebrew University Medical School, IMRIC, Jerusalem, Israel
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The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing
- Einat Seidel,
- Liat Dassa,
- Corinna Schuler,
- Esther Oiknine-Djian,
- Dana G. Wolf,
- Vu Thuy Khanh Le-Trilling,
- Ofer Mandelboim
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- Published: May 3, 2021
- https://doi.org/10.1371/journal.ppat.1008807