A HSV1 mutant leads to an attenuated phenotype and induces immunity with a protective effect

Xingli Xu; Xiao Feng; Lichun Wang; Ting Yi; Lichun Zheng; Guorun Jiang; Shengtao Fan; Yun Liao; Min Feng; Ying Zhang; Dandan Li; Qihan Li

doi:10.1371/journal.ppat.1008703

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Open Access

Peer-reviewed

Research Article

A HSV1 mutant leads to an attenuated phenotype and induces immunity with a protective effect

Xingli Xu,

Roles Formal analysis, Funding acquisition, Methodology, Project administration, Software, Supervision, Validation, Writing – original draft

Affiliation Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases, Kunming, China
⨯
Xiao Feng,

Roles Formal analysis, Methodology

Affiliation Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases, Kunming, China
⨯
Lichun Wang,

Roles Methodology

Affiliation Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases, Kunming, China
⨯
Ting Yi,

Roles Methodology

Affiliation Weirui Biotechnology (Kunming) Co., Ltd, Kunming, China
⨯
Lichun Zheng,

Roles Formal analysis

Affiliation Weirui Biotechnology (Kunming) Co., Ltd, Kunming, China
⨯
Guorun Jiang,

Roles Methodology

Affiliation Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases, Kunming, China
⨯
Shengtao Fan,

Roles Formal analysis, Software

Affiliation Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases, Kunming, China
⨯
Yun Liao,

Roles Methodology

Affiliation Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases, Kunming, China
⨯
Min Feng,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliation Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases, Kunming, China
⨯
Ying Zhang,

Roles Formal analysis, Funding acquisition, Software

Affiliation Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases, Kunming, China
⨯
Dandan Li,

Roles Formal analysis

Affiliation Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases, Kunming, China

http://orcid.org/0000-0002-3527-3522

⨯
Qihan Li

Roles Funding acquisition, Project administration, Supervision, Validation, Writing – review & editing

* E-mail: liqihan@imbcams.com.cn

Affiliation Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases, Kunming, China

http://orcid.org/0000-0002-8932-4516

⨯

A HSV1 mutant leads to an attenuated phenotype and induces immunity with a protective effect

Xingli Xu,
Xiao Feng,
Lichun Wang,
Ting Yi,
Lichun Zheng,
Guorun Jiang,
Shengtao Fan,
Yun Liao,
Min Feng,
Ying Zhang

Published: August 10, 2020
https://doi.org/10.1371/journal.ppat.1008703

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