Synthetic DNA and biosecurity: Nuances of predicting pathogenicity and the impetus for novel computational approaches for screening oligonucleotides

• R. A. Leo Elworth ,

  Contributed equally to this work with: R. A. Leo Elworth, Christian Diaz

  Affiliation Department of Computer Science, Rice University, Houston, Texas, United States of America

  http://orcid.org/0000-0002-3945-0661

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• Christian Diaz ,

  Contributed equally to this work with: R. A. Leo Elworth, Christian Diaz

  Affiliation Department of Computer Science, Rice University, Houston, Texas, United States of America

  ⨯
• Jing Yang,

  Affiliation Department of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, Bryan, Texas, United States of America

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• Paul de Figueiredo,

  Affiliations Department of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, Bryan, Texas, United States of America, Department of Veterinary Pathobiology, Texas A&M University, College Station, Texas, United States of America, Norman Borlaug Center, Texas A&M University, College Station, Texas, United States of America

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• Krista Ternus ,

  ¶‡ These authors contributed equally to the supervision of this work.

  Affiliation Signature Science, LLC, Austin, Texas, United States of America

  http://orcid.org/0000-0003-1138-5308

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• Todd Treangen

  * E-mail: treangen@rice.edu

  ¶‡ These authors contributed equally to the supervision of this work.

  Affiliation Department of Computer Science, Rice University, Houston, Texas, United States of America

  http://orcid.org/0000-0002-3760-564X

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