DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction

• Pan Pan ,

  Contributed equally to this work with: Pan Pan, Geng Li

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Writing – original draft

  Affiliations Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China, The First Affiliated Hospital of Jinan University, Guangzhou, China

  ⨯
• Geng Li ,

  Contributed equally to this work with: Pan Pan, Geng Li

  Roles Conceptualization, Investigation, Methodology, Resources, Validation, Writing – original draft, Writing – review & editing

  Affiliations Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China, State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China, Center for Animal Experiment, Guangzhou University of Chinese Medicine, Guangzhou, China

  ⨯
• Miaomiao Shen,

  Roles Formal analysis, Methodology, Resources, Validation

  Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China

  ⨯
• Zhenyang Yu,

  Roles Formal analysis, Investigation, Methodology, Resources, Validation

  Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China

  ⨯
• Weiwei Ge,

  Roles Data curation, Investigation, Methodology, Resources, Validation

  Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China

  ⨯
• Zizhao Lao,

  Roles Formal analysis, Methodology, Resources, Validation

  Affiliation Center for Animal Experiment, Guangzhou University of Chinese Medicine, Guangzhou, China

  ⨯
• Yaohua Fan,

  Roles Formal analysis, Methodology, Resources, Visualization

  Affiliation Center for Animal Experiment, Guangzhou University of Chinese Medicine, Guangzhou, China

  ⨯
• Keli Chen,

  Roles Data curation, Formal analysis, Investigation, Visualization

  Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China

  ⨯
• Zhihao Ding,

  Roles Formal analysis, Methodology, Resources, Validation

  Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China

  ⨯
• Wenbiao Wang,

  Roles Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliation Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China

  ⨯
• Pin Wan,

  Roles Formal analysis, Investigation, Resources, Validation

  Affiliation Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China

  ⨯
• Muhammad Adnan Shereen,

  Roles Data curation, Investigation, Methodology, Validation

  Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China

  ⨯
• Zhen Luo,

  Roles Data curation, Investigation, Resources, Validation

  Affiliations Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China, Foshan Institute of Medical Microbiology, Foshan, China

  https://orcid.org/0000-0002-1142-2845

  ⨯
• Xulin Chen,

  Roles Data curation, Methodology, Resources, Visualization

  Affiliations Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China, Foshan Institute of Medical Microbiology, Foshan, China

  ⨯
• Qiwei Zhang,

  Roles Data curation, Methodology, Resources, Visualization

  Affiliations Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China, Foshan Institute of Medical Microbiology, Foshan, China

  https://orcid.org/0000-0002-2770-111X

  ⨯
• Luping Lin ,

  Roles Conceptualization, Formal analysis, Investigation, Resources, Validation, Writing – original draft

  * E-mail: linlupingdoctor@qq.com (LL); jwu898@jnu.edu.cn (JW)

  Affiliations Center for Animal Experiment, Guangzhou University of Chinese Medicine, Guangzhou, China, Guangzhou Eighth People’s Hospital, Guangzhou, China

  ⨯
•  [ ... ],
• Jianguo Wu

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: linlupingdoctor@qq.com (LL); jwu898@jnu.edu.cn (JW)

  Affiliations Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China, The First Affiliated Hospital of Jinan University, Guangzhou, China, State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China, Foshan Institute of Medical Microbiology, Foshan, China

  https://orcid.org/0000-0002-8326-2895

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